Cisplatin

tumor protein p53 ; Homo sapiens







886 Article(s)
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1 34597653 Combination of Compound Kushen Injection and cisplatin shows synergistic antitumor activity in p53-R273H/P309S mutant colorectal cancer cells through inducing apoptosis. 2022 Jan 30 1
2 34994335 Novel coumarin derivatives containing a triazole moiety: A study on synthesis, cytotoxicity, membrane dysfunction, apoptosis, cell cycle, and antiangiogenic studies. 2022 Jan 6 1
3 34995485 Caffeic acid phenethyl ester targets ubiquitin-specific protease 8 and synergizes with cisplatin in endometrioid ovarian carcinoma cells. 2022 Mar 1
4 35073843 Epigenetic landscape of drug responses revealed through large-scale ChIP-seq data analyses. 2022 Jan 24 1
5 35167826 Cisplatin toxicity in the developing brain displays an absolute requirement for caspase-3. 2022 May 1
6 35205642 Activation of ABCC Genes by Cisplatin Depends on the CoREST Occurrence at Their Promoters in A549 and MDA-MB-231 Cell Lines. 2022 Feb 11 1
7 35328718 p62 Promotes the Mitochondrial Localization of p53 through Its UBA Domain and Participates in Regulating the Sensitivity of Ovarian Cancer Cells to Cisplatin. 2022 Mar 18 3
8 35346500 NDC80 Enhances Cisplatin-resistance in Triple-negative Breast Cancer. 2022 Jun 1
9 35456022 Apoptotic and DNA Damage Effect of 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose in Cisplatin-Resistant Non-Small Lung Cancer Cells via Phosphorylation of H2AX, CHK2 and p53. 2022 Apr 14 1
10 35468881 JMJD2C mediates the MDM2/p53/IL5RA axis to promote CDDP resistance in uveal melanoma. 2022 Apr 25 1
11 35487028 New insights into the interactions of HPV-16 E6*I and E6*II with p53 isoforms and induction of apoptosis in cancer-derived cell lines. 2022 Jun 3
12 35522909 Exosome-transmitted miR-769-5p confers cisplatin resistance and progression in gastric cancer by targeting CASP9 and promoting the ubiquitination degradation of p53. 2022 May 2
13 35608342 A Critical Role for p53 during the HPV16 Life Cycle. 2022 May 24 1
14 35636434 Melatonin Increases the Sensitivity of Osteosarcoma Cells to Chemotherapy Drug Cisplatin. 2022 May 30 2
15 32757802 Apigenin Enhanced Antitumor Effect of Cisplatin in Lung Cancer via Inhibition of Cancer Stem Cells. 2021 5
16 33183422 Effect of Nano-Platinum on Proliferation and Apoptosis of Non-Small Cell Lung Cancer Cells via P53 Pathway. 2021 Feb 1 1
17 33240412 Blockade of TRIM59 enhances esophageal cancer cell chemosensitivity to cisplatin by upregulating p53. 2021 Jan 4
18 33390811 LncRNA XIST acts as a MicroRNA-520 sponge to regulate the Cisplatin resistance in NSCLC cells by mediating BAX through CeRNA network. 2021 1
19 33456714 Correction: Cepharanthine hydrochloride reverses the mdr1 (P-glycoprotein)-mediated esophageal squamous cell carcinoma cell cisplatin resistance through JNK and p53 signals. 2021 Jan 5 1
20 33473103 p53 is required for nuclear but not mitochondrial DNA damage-induced degeneration. 2021 Jan 20 1
21 33530952 Inhibition of Kpnβ1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer. 2021 Feb 2 1
22 33627632 Mutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane. 2021 Feb 24 1
23 33650658 Circadian clock protein CRY1 prevents paclitaxel‑induced senescence of bladder cancer cells by promoting p53 degradation. 2021 Mar 1
24 33669781 Mechanisms of Cisplatin in Combination with Repurposed Drugs against Human Endometrial Carcinoma Cells. 2021 Feb 19 1
25 33705152 Synergistic Therapy for Cervical Cancer by Codelivery of Cisplatin and JQ1 Inhibiting Plk1-Mutant Trp53 Axis. 2021 Mar 24 1
26 33773191 Bibenzyl analogue DS-1 inhibits MDM2-mediated p53 degradation and sensitizes apoptosis in lung cancer cells. 2021 May 2
27 33850897 A metabolism-related gene signature for predicting the prognosis and therapeutic responses in patients with hepatocellular carcinoma. 2021 Mar 1
28 33868388 Interplay Between Thiamine and p53/p21 Axes Affects Antiproliferative Action of Cisplatin in Lung Adenocarcinoma Cells by Changing Metabolism of 2-Oxoglutarate/Glutamate. 2021 4
29 33906321 Epigallocatechin Gallate Enhances Inhibition Effect of DDP on the Proliferation of Gastric Cancer BGC-823 Cells by Regulating p19Arf-p53-p21Cip1 Signaling Pathway. 2021 Apr 1 1
30 33907694 Rapidly Progressing Urothelial Carcinoma Due to a Rare TP53 (p.Arg110Pro) Mutation: A Case Report and Review of the Literature. 2021 1
31 33922989 Platinum Complexes in Colorectal Cancer and Other Solid Tumors. 2021 Apr 25 1
32 33952795 Inhibitory Effect of Astragalus Polysaccharide Combined with Cisplatin on Cell Cycle and Migration of Nasopharyngeal Carcinoma Cell Lines. 2021 Jul 1 1
33 33990641 trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway. 2021 May 14 3
34 34063628 Jorunnamycin A Suppresses Stem-Like Phenotypes and Sensitizes Cisplatin-Induced Apoptosis in Cancer Stem-Like Cell-Enriched Spheroids of Human Lung Cancer Cells. 2021 May 3 1
35 34165168 MicroRNA‑10b modulates cisplatin tolerance by targeting p53 directly in lung cancer cells. 2021 Aug 7
36 34183962 The Synergistic Combination of Cisplatin and Piperine Induces Apoptosis in MCF-7 Cell Line. 2021 May 3
37 34204834 Resveratrol Modulation of Apoptosis and Cell Cycle Response to Cisplatin in Head and Neck Cancer Cell Lines. 2021 Jun 12 2
38 34212455 Antitumor effect of WEE1 blockade as monotherapy or in combination with cisplatin in urothelial cancer. 2021 Sep 5
39 34261004 Cisplatin's potential for type 2 diabetes repositioning by inhibiting CDKN1A, FAS, and SESN1. 2021 Aug 1
40 34281219 The Enigmatic Role of TP53 in Germ Cell Tumours: Are We Missing Something? 2021 Jul 2 3
41 34445588 Molecular Mechanisms of Chemoresistance Induced by Cisplatin in NSCLC Cancer Therapy. 2021 Aug 18 2
42 34528900 Metformin-induced chemosensitization to cisplatin depends on P53 status and is inhibited by Jarid1b overexpression in non-small cell lung cancer cells. 2021 Sep 16 5
43 34731023 Cisplatin Chemotherapy and Cochlear Damage: Otoprotective and Chemosensitization Properties of Polyphenols. 2021 Dec 17 1
44 34769213 The Role of TP53 in Cisplatin Resistance in Mediastinal and Testicular Germ Cell Tumors. 2021 Oct 29 5
45 34822033 USP39 attenuates the antitumor activity of cisplatin on colon cancer cells dependent on p53. 2021 Nov 25 4
46 34832966 In Vitro Assessment of the Role of p53 on Chemotherapy Treatments in Neuroblastoma Cell Lines. 2021 Nov 19 1
47 34876239 Comparison of cisplatin-induced anti-tumor response in CT26 syngeneic tumors of three BALB/c substrains. 2021 Dec 8 1
48 34915755 A nano based approach to alleviate cisplatin induced nephrotoxicity. 2021 Jan-Dec 1
49 35070983 Prediction of the Mechanisms by Which Quercetin Enhances Cisplatin Action in Cervical Cancer: A Network Pharmacology Study and Experimental Validation. 2021 1
50 31841768 Towards the overcoming of anticancer drug resistance mediated by p53 mutations. 2020 Mar 1