Cisplatin

MYC proto-oncogene, bHLH transcription factor ; Homo sapiens







88 Article(s)
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1 35173547 HJURP Promotes Malignant Progression and Mediates Sensitivity to Cisplatin and WEE1-inhibitor in Serous Ovarian Cancer. 2022 1
2 35626088 Preclinical Head and Neck Squamous Cell Carcinoma Models for Combined Targeted Therapy Approaches. 2022 May 18 1
3 34204834 Resveratrol Modulation of Apoptosis and Cell Cycle Response to Cisplatin in Head and Neck Cancer Cell Lines. 2021 Jun 12 2
4 34232919 Antiparasitic mebendazole (MBZ) effectively overcomes cisplatin resistance in human ovarian cancer cells by inhibiting multiple cancer-associated signaling pathways. 2021 Jul 7 1
5 34769137 PR-619, a General Inhibitor of Deubiquitylating Enzymes, Diminishes Cisplatin Resistance in Urothelial Carcinoma Cells through the Suppression of c-Myc: An In Vitro and In Vivo Study. 2021 Oct 28 1
6 34948122 New Synthetic Lethality Re-Sensitizing Platinum-Refractory Cancer Cells to Cisplatin In Vitro: The Rationale to Co-Use PARP and ATM Inhibitors. 2021 Dec 11 2
7 35070983 Prediction of the Mechanisms by Which Quercetin Enhances Cisplatin Action in Cervical Cancer: A Network Pharmacology Study and Experimental Validation. 2021 1
8 31765939 Glutamine deprivation counteracts hypoxia-induced chemoresistance. 2020 Jan 1
9 31821542 Cisplatin-mediated down-regulation of miR-145 contributes to up-regulation of PD-L1 via the c-Myc transcription factor in cisplatin-resistant ovarian carcinoma cells. 2020 Apr 1
10 32319562 Although c‑MYC contributes to tamoxifen resistance, it improves cisplatin sensitivity in ER‑positive breast cancer. 2020 Apr 3
11 32626933 High expression of FUSE binding protein 1 in breast cancer stimulates cell proliferation and diminishes drug sensitivity. 2020 Aug 2
12 32710593 Pluripotency transcription factor Nanog and its association with overall oral squamous cell carcinoma progression, cisplatin-resistance, invasion and stemness acquisition. 2020 Nov 1
13 32725721 Ascorbate sensitizes human osteosarcoma cells to the cytostatic effects of cisplatin. 2020 Aug 1
14 33089188 Potential Role of DEC1 in Cervical Cancer Cells Involving Overexpression and Apoptosis. 2020 Mar 1
15 33488948 Novel strategies to target chemoresistant triple-negative breast cancer. 2020 Dec 31 1
16 30166592 miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer. 2019 Jan 7
17 30210134 Gemcitabine, Dexamethasone, and Cisplatin Regimen as an Effective Salvage Therapy for High-grade B-cell Lymphoma with MYC and BCL2 and/or BCL6 Rearrangements. 2019 Feb 15 1
18 30668336 Ailanthone inhibits cell growth and migration of cisplatin resistant bladder cancer cells through down-regulation of Nrf2, YAP, and c-Myc expression. 2019 Mar 15 2
19 30825244 c-Myc mediated upregulation of long noncoding RNA SNHG12 regulates proliferation and drug sensitivity in natural killer/T-cell lymphoma. 2019 Aug 4
20 31186712 Co-inhibition of BMI1 and Mel18 enhances chemosensitivity of esophageal squamous cell carcinoma in vitro and in vivo. 2019 Jun 1
21 31432162 Cisplatin decreases cyclin D2 expression via upregulating miR‑93 to inhibit lung adenocarcinoma cell growth. 2019 Oct 1
22 31632022 Exosomal Transfer Of Cisplatin-Induced miR-425-3p Confers Cisplatin Resistance In NSCLC Through Activating Autophagy. 2019 1
23 31727874 Cisplatin exposure causes c-Myc-dependent resistance to CDK4/6 inhibition in HPV-negative head and neck squamous cell carcinoma. 2019 Nov 14 5
24 31761897 Forkhead Box R2 Knockdown Decreases Chemoresistance to Cisplatin via MYC Pathway in Bladder Cancer. 2019 Nov 25 2
25 31933859 Silencing long non-coding RNA NEAT1 enhances the suppression of cell growth, invasion, and apoptosis of bladder cancer cells under cisplatin chemotherapy. 2019 1
26 29257330 Niclosamide enhances the cytotoxic effect of cisplatin in cisplatin-resistant human lung cancer cells via suppression of lung resistance-related protein and c-myc. 2018 Mar 2
27 29286162 GC7 enhances cisplatin sensitivity via STAT3 signaling pathway inhibition and eIF5A2 inactivation in mesenchymal phenotype oral cancer cells. 2018 Mar 2
28 30071534 HDAC1 Silencing in Ovarian Cancer Enhances the Chemotherapy Response. 2018 5
29 30443189 Effect of RIF1 on response of non-small-cell lung cancer patients to platinum-based chemotherapy by regulating MYC signaling pathway. 2018 4
30 28076844 Sulforaphane inhibits cancer stem-like cell properties and cisplatin resistance through miR-214-mediated downregulation of c-MYC in non-small cell lung cancer. 2017 Feb 14 2
31 28590415 The Dual Roles of MYC in Genomic Instability and Cancer Chemoresistance. 2017 Jun 7 1
32 28623290 TCRP1 transcriptionally regulated by c-Myc confers cancer chemoresistance in tongue and lung cancer. 2017 Jun 16 1
33 28817737 Myc mediates cancer stem-like cells and EMT changes in triple negative breast cancers cells. 2017 4
34 28878262 Hyper-O-GlcNAcylation induces cisplatin resistance via regulation of p53 and c-Myc in human lung carcinoma. 2017 Sep 6 3
35 29029460 VRK1 promotes cisplatin resistance by up-regulating c-MYC via c-Jun activation and serves as a therapeutic target in esophageal squamous cell carcinoma. 2017 Sep 12 3
36 29060932 miR-34a increases cisplatin sensitivity of osteosarcoma cells in vitro through up-regulation of c-Myc and Bim signal. 2017 Dec 12 3
37 29098029 Synergistic anti-proliferative and pro-apoptotic activities of 5F and cisplatin in human non-small cell lung cancer NCI-H23 cells. 2017 Nov 1
38 29254192 Inhibition of coiled coil domain containing protein 69 enhances platinum-induced apoptosis in ovarian cancer cells. 2017 Nov 24 1
39 26392091 Influence of selected anti-cancer drugs on the induction of DNA double-strand breaks and changes in gene expression in human hepatoma HepG2 cells. 2016 Aug 1
40 27110775 Smad3 Sensitizes Hepatocelluar Carcinoma Cells to Cisplatin by Repressing Phosphorylation of AKT. 2016 Apr 22 1
41 27492148 PKM2 enhances chemosensitivity to cisplatin through interaction with the mTOR pathway in cervical cancer. 2016 Aug 5 1
42 27765932 Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation. 2016 Dec 13 2
43 25411027 Sequential treatment with aurora B inhibitors enhances cisplatin-mediated apoptosis via c-Myc. 2015 Apr 5
44 25748238 Erlotinib-cisplatin combination inhibits growth and angiogenesis through c-MYC and HIF-1α in EGFR-mutated lung cancer in vitro and in vivo. 2015 Feb 2
45 25796504 Cisplatin-mediated c-myc overexpression and cytochrome c (cyt c) release result in the up-regulation of the death receptors DR4 and DR5 and the activation of caspase 3 and caspase 9, likely responsible for the TRAIL-sensitizing effect of cisplatin. 2015 Apr 4
46 26227489 Targeting c-MYC in Platinum-Resistant Ovarian Cancer. 2015 Oct 4
47 24926545 Frequent coamplification and cooperation between C-MYC and PVT1 oncogenes promote malignant pleural mesothelioma. 2014 Jul 1
48 25131138 C-Myc participates in β-catenin-mediated drug resistance in A549/DDP lung adenocarcinoma cells. 2014 Dec 5
49 23685757 Effects of combined c-myc and Bmi-1 siRNAs on the growth and chemosensitivity of MG-63 osteosarcoma cells. 2013 Jul 1
50 23879689 A role for the copper transporter Ctr1 in the synergistic interaction between hyperthermia and cisplatin treatment. 2013 Sep 1