Cisplatin

NFE2 like bZIP transcription factor 2 ; Homo sapiens







118 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34264023 HO-1 in lymph node metastasis predicted overall survival in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiation therapy. 2022 Mar 1
2 34856444 Cyclometalated Ru(II)-isoquinoline complexes overcome cisplatin resistance of A549/DDP cells by downregulation of Nrf2 via Akt/GSK-3β/Fyn pathway. 2022 Feb 1
3 35327653 The Impact of NRF2 Inhibition on Drug-Induced Colon Cancer Cell Death and p53 Activity: A Pilot Study. 2022 Mar 17 5
4 35464301 All-trans-retinoic acid induces RARB-dependent apoptosis via ROS induction and enhances cisplatin sensitivity by NRF2 downregulation in cholangiocarcinoma cells. 2022 Jun 5
5 35468014 Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway. 2022 Feb 2
6 35490795 Induction of ferroptosis by carnosic acid-mediated inactivation of Nrf2/HO-1 potentiates cisplatin responsiveness in OSCC cells. 2022 Apr 29 6
7 35505963 miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways. 2022 Jun 14 1
8 35580917 Vinpocetine enhances cisplatin sensitivity of non-small cell lung cancer cells by reducing the nuclear factor erythroid 2-related factor 2 signaling. 2022 May 17 2
9 35626727 Activation of MT1/MT2 to Protect Testes and Leydig Cells against Cisplatin-Induced Oxidative Stress through the SIRT1/Nrf2 Signaling Pathway. 2022 May 19 1
10 33148531 Trigonelline inhibits Nrf2 via EGFR signalling pathway and augments efficacy of Cisplatin and Etoposide in NSCLC cells. 2021 Feb 1
11 33219317 UFBP1, a key component in ufmylation, enhances drug sensitivity by promoting proteasomal degradation of oxidative stress-response transcription factor Nrf2. 2021 Jan 1
12 33610575 Vincamine protects against cisplatin induced nephrotoxicity via activation of Nrf2/HO-1 and hindering TLR4/ IFN-γ/CD44 cells inflammatory cascade. 2021 May 1 1
13 33735393 Sensitization of A-549 lung cancer cells to Cisplatin by Quinacrine-loaded lipidic nanoparticles via suppressing Nrf2 mediated defense mechanism. 2021 Jul 2
14 33771701 Nrf2 signaling pathway in cisplatin chemotherapy: Potential involvement in organ protection and chemoresistance. 2021 May 1
15 34080212 Combination of cyanidin-3-O-glucoside and cisplatin induces oxidative stress and apoptosis in HeLa cells by reducing activity of endogenous antioxidants, increasing bax/bcl-2 mRNA expression ratio, and downregulating Nrf2 expression. 2021 Jul 1
16 34098867 Induction of ferroptosis by ATF3 elevation alleviates cisplatin resistance in gastric cancer by restraining Nrf2/Keap1/xCT signaling. 2021 Jun 7 3
17 34237431 Cisplatin synergizes with PRLX93936 to induce ferroptosis in non-small cell lung cancer cells. 2021 Sep 10 1
18 34239803 Activation of MEK1/2/Nrf-2 Signaling Pathway by Epstein-Barr Virus-Latent Membrane Protein 1 Enhances Autophagy and Cisplatin Resistance in T-Cell Lymphoma. 2021 2
19 34320371 The developmental origin of cancers defines basic principles of cisplatin resistance. 2021 Oct 28 1
20 34407971 Recurrent Human Papillomavirus-Related Head and Neck Cancer Undergoes Metabolic Reprogramming and Is Driven by Oxidative Phosphorylation. 2021 Nov 15 1
21 34673143 Thioredoxin reductase-1 levels are associated with NRF2 pathway activation and tumor recurrence in non-small cell lung cancer. 2021 Dec 1
22 34786050 Bladder cancer cells prevent cisplatin-induced oxidative stress by upregulating Nestin1 expression. 2021 1
23 30787448 Expression profile and bioinformatics analysis of COMMD10 in BALB/C mice and human. 2020 Apr 1
24 31583720 Deregulation of UCA1 expression may be involved in the development of chemoresistance to cisplatin in the treatment of non-small-cell lung cancer via regulating the signaling pathway of microRNA-495/NRF2. 2020 Apr 2
25 31791583 MBNL1 regulates resistance of HeLa cells to cisplatin via Nrf2. 2020 Feb 12 2
26 31897145 Erastin/sorafenib induces cisplatin-resistant non-small cell lung cancer cell ferroptosis through inhibition of the Nrf2/xCT pathway. 2020 Jan 6
27 31974389 The dual role of curcumin and ferulic acid in counteracting chemoresistance and cisplatin-induced ototoxicity. 2020 Jan 23 1
28 31983246 Thymoquinone and curcumin combination protects cisplatin-induced kidney injury, nephrotoxicity by attenuating NFκB, KIM-1 and ameliorating Nrf2/HO-1 signalling. 2020 Nov 2
29 32012470 MicroRNA-153-3p regulates cell proliferation and cisplatin resistance via Nrf-2 in esophageal squamous cell carcinoma. 2020 Mar 4
30 32088177 Bisdemethoxycurcumin attenuates cisplatin-induced renal injury through anti-apoptosis, anti-oxidant and anti-inflammatory. 2020 May 5 2
31 32092292 Inhibition of thioredoxin reductase 1 correlates with platinum-based chemotherapeutic induced tissue injury. 2020 May 1
32 32102425 Non-Phosphorylatable PEA-15 Sensitises SKOV-3 Ovarian Cancer Cells to Cisplatin. 2020 Feb 24 2
33 32206093 Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer. 2020 1
34 32394538 Cytoplasmic, but not nuclear Nrf2 expression, is associated with inferior survival and relapse rate and response to platinum-based chemotherapy in non-small cell lung cancer. 2020 Jul 3
35 32428544 Nrf2 activation protects auditory hair cells from cisplatin-induced ototoxicity independent on mitochondrial ROS production. 2020 Oct 1 7
36 32574971 The effect of monotropein on alleviating cisplatin-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis. 2020 Sep 1
37 32800561 Baicalein enhanced cisplatin sensitivity of gastric cancer cells by inducing cell apoptosis and autophagy via Akt/mTOR and Nrf2/Keap 1 pathway. 2020 Oct 20 1
38 32814771 Chemotherapeutic resistance of head and neck squamous cell carcinoma is mediated by EpCAM induction driven by IL-6/p62 associated Nrf2-antioxidant pathway activation. 2020 Aug 20 2
39 32817372 GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma. 2020 Aug 18 1
40 32927432 Metformin suppresses Nrf2-mediated chemoresistance in hepatocellular carcinoma cells by increasing glycolysis. 2020 Sep 14 1
41 32945421 Panax notoginseng Saponins protect auditory cells against cisplatin‑induced ototoxicity by inducing the AKT/Nrf2 signaling‑mediated redox pathway. 2020 Oct 2
42 33041661 Stigmasterol sensitizes endometrial cancer cells to chemotherapy by repressing Nrf2 signal pathway. 2020 1
43 33066634 Carbosilane Dendrimers Loaded with siRNA Targeting Nrf2 as a Tool to Overcome Cisplatin Chemoresistance in Bladder Cancer Cells. 2020 Oct 14 4
44 33232319 LncRNA MIR4435-2HG mediates cisplatin resistance in HCT116 cells by regulating Nrf2 and HO-1. 2020 3
45 33290263 Enhancer-bound Nrf2 licenses HIF-1α transcription under hypoxia to promote cisplatin resistance in hepatocellular carcinoma cells. 2020 Dec 3 6
46 33294122 The Nrf2/PGC1α Pathway Regulates Antioxidant and Proteasomal Activity to Alter Cisplatin Sensitivity in Ovarian Cancer. 2020 1
47 33489797 Metformin reverses chemoresistance in non-small cell lung cancer via accelerating ubiquitination-mediated degradation of Nrf2. 2020 Dec 2
48 30030687 NRAL mediates cisplatin resistance in hepatocellular carcinoma via miR-340-5p/Nrf2 axis. 2019 Mar 5
49 30668336 Ailanthone inhibits cell growth and migration of cisplatin resistant bladder cancer cells through down-regulation of Nrf2, YAP, and c-Myc expression. 2019 Mar 15 4
50 30811078 The induction of ferroptosis by impairing STAT3/Nrf2/GPx4 signaling enhances the sensitivity of osteosarcoma cells to cisplatin. 2019 Nov 3