Cisplatin

ATP binding cassette subfamily C member 2 ; Homo sapiens







70 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35307915 Overexpression of Tetraspanin31 contributes to malignant potential and poor outcomes in gastric cancer. 2022 Jun 1
2 32815556 Increased ABCC2 expression predicts cisplatin resistance in non-small cell lung cancer. 2021 Mar 6
3 32918990 Kanglaite enhances the efficacy of cisplatin in suppression of hepatocellular carcinoma via inhibiting CKLF1 mediated NF-κB pathway and regulating transporter mediated drug efflux. 2021 Jan 10 1
4 33390536 Functional Alterations of Multidrug Resistance-Associated Proteins 2 and 5, and Breast Cancer Resistance Protein upon Snail-Induced Epithelial-Mesenchymal Transition in HCC827 Cells. 2021 1
5 34399762 Nitric oxide-releasing micelles with intelligent targeting for enhanced anti-tumor effect of cisplatin in hypoxia. 2021 Aug 16 2
6 31926942 ISG15 suppresses translation of ABCC2 via ISGylation of hnRNPA2B1 and enhances drug sensitivity in cisplatin resistant ovarian cancer cells. 2020 Apr 1
7 32037720 Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cells. 2020 Apr 1
8 32377314 Renoprotective Effects of a New Free Radical Scavenger, XH-003, against Cisplatin-Induced Nephrotoxicity. 2020 2
9 31646427 Encapsulation of crocetin into poly (lactic-co-glycolic acid) nanoparticles overcomes drug resistance in human ovarian cisplatin-resistant carcinoma cell line (A2780-RCIS). 2019 Dec 1
10 29848100 Ovarian cancer cells cisplatin sensitization agents selected by mass cytometry target ABCC2 inhibition. 2018 Jun 1 2
11 27435393 Inhibition of the EGFR/STAT3/CEBPD Axis Reverses Cisplatin Cross-resistance with Paclitaxel in the Urothelial Carcinoma of the Urinary Bladder. 2017 Jan 15 1
12 28386339 MiR-490-3p sensitizes ovarian cancer cells to cisplatin by directly targeting ABCC2. 2017 2
13 28422153 Clinical-pharmacogenetic models for personalized cancer treatment: application to malignant mesothelioma. 2017 Apr 19 1
14 28423482 Clerosterol from vinegar-baked radix bupleuri modifies drug transport. 2017 Mar 28 1
15 29069816 Ubenimex suppresses Pim-3 kinase expression by targeting CD13 to reverse MDR in HCC cells. 2017 Sep 22 1
16 29299132 Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters. 2017 Dec 15 1
17 26721606 Proadifen sensitizes resistant ovarian adenocarcinoma cells to cisplatin. 2016 Jan 22 1
18 27330316 Combination of gambogic acid with cisplatin enhances the antitumor effects on cisplatin-resistant lung cancer cells by downregulating MRP2 and LRP expression. 2016 4
19 27602148 Enhancing chemosensitivity in oral squamous cell carcinoma by lentivirus vector-mediated RNA interference targeting EGFR and MRP2. 2016 Sep 8
20 25554586 Report of new haplotype for ABCC2 gene: rs17222723 and rs8187718 in cis. 2015 Mar 1
21 26239260 Valproic acid suppresses the self-renewal and proliferation of head and neck cancer stem cells. 2015 Oct 1
22 26295158 Multidrug Resistance-Associated Protein 2 Expression Is Upregulated by Adenosine 5'-Triphosphate in Colorectal Cancer Cells and Enhances Their Survival to Chemotherapeutic Drugs. 2015 1
23 24641901 Transgenic expression of the human MRP2 transporter reduces cisplatin accumulation and nephrotoxicity in Mrp2-null mice. 2014 May 4
24 24913304 A cisplatin-resistant head and neck cancer cell line with cytoplasmic p53(mut) exhibits ATP-binding cassette transporter upregulation and high glutathione levels. 2014 Oct 1
25 23381786 Camptothecin and cisplatin upregulate ABCG2 and MRP2 expression by activating the ATM/NF-κB pathway in lung cancer cells. 2013 Apr 3
26 23420099 Factors affecting the sensitivity of human-derived esophageal carcinoma cell lines to 5-fluorouracil and cisplatin. 2013 Feb 2
27 23876835 Epigallocatechin-3-gallate attenuates head and neck cancer stem cell traits through suppression of Notch pathway. 2013 Oct 1
28 24041618 Combination of arsenic trioxide and chemotherapy in small cell lung cancer. 2013 Nov 1
29 24400442 Let-7c sensitizes acquired cisplatin-resistant A549 cells by targeting ABCC2 and Bcl-XL. 2013 Dec 1
30 22534871 Associations between ABCC2 polymorphisms and cisplatin disposition and efficacy. 2012 Jun 4
31 22800197 Cisplatin-induced chemoresistance in colon cancer cells involves FXR-dependent and FXR-independent up-regulation of ABC proteins. 2012 Sep 4 4
32 21206495 Role of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma. 2011 Feb 15 4
33 21687948 'Genetic profiling' and ovarian cancer therapy (review). 2011 Sep-Oct 1
34 20204280 Multidrug resistance-associated protein 2 determines the efficacy of cisplatin in patients with hepatocellular carcinoma. 2010 Apr 6
35 20331629 Quantitative analysis of cisplatin sensitivity of human esophageal squamous cancer cell lines using in-air micro-PIXE. 2010 Jun 1
36 20628484 Association of ABCC2 and CDDP-Resistance in Two Sublines Resistant to CDDP Derived from a Human Nasopharyngeal Carcinoma Cell Line. 2010 12
37 20013091 Radiation- and chemoinduced multidrug resistance in colon carcinoma cells. 2009 Dec 1
38 18834541 Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin. 2008 Oct 4 5
39 19020751 Expression of multidrug resistance-associated protein 2 is involved in chemotherapy resistance in human pancreatic cancer. 2008 Dec 12
40 17190787 Characteristic expression of Lewis-antigenic glycolipids in human ovarian carcinoma-derived cells with anticancer drug-resistance. 2007 Mar 1
41 17276588 Interaction between CD44 and hyaluronate induces chemoresistance in non-small cell lung cancer cell. 2007 Jul 18 1
42 17704753 Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-ABCC2 antisense constructs. 2007 Nov 1
43 16213010 MRP2 (ABCC2) and cisplatin sensitivity in hepatocytes and human ovarian carcinoma. 2006 Feb 8
44 16341694 Increased sensitivity of Hep G2 cells toward the cytotoxicity of cisplatin by the treatment of piper betel leaf extract. 2006 Jun 3
45 16831027 Immunoexpression of multidrug-resistance protein 2 and cyclooxygenase 2 in medullary thyroid carcinomas. 2006 Jul 1
46 16876126 RNA interference-triggered reversal of ABCC2-dependent cisplatin resistance in human cancer cells. 2006 Sep 15 6
47 16995873 Characteristic expression of globotriaosyl ceramide in human ovarian carcinoma-derived cells with anticancer drug resistance. 2006 Dec 1
48 17145840 ABCC2 (MRP2, cMOAT) can be localized in the nuclear membrane of ovarian carcinomas and correlates with resistance to cisplatin and clinical outcome. 2006 Dec 1 5
49 15688364 Protection of platinum-DNA adduct formation and reversal of cisplatin resistance by anti-MRP2 hammerhead ribozymes in human cancer cells. 2005 Jun 20 2
50 16080518 Involvement of ABC transporters in chemosensitivity of human renal cell carcinoma, and regulation of MRP2 expression by conjugated bilirubin. 2005 Jul-Aug 1