Cisplatin

cytochrome c, somatic ; Homo sapiens







82 Article(s)
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1 35204233 Lysophosphatidic Acid Receptor 3 Promotes Mitochondrial Homeostasis against Oxidative Stress: Potential Therapeutic Approaches for Hutchinson-Gilford Progeria Syndrome. 2022 Feb 10 1
2 33929634 Resistin increases cisplatin-induced cytotoxicity in lung adenocarcinoma A549 cells via a mitochondria-mediated pathway. 2021 Apr 30 1
3 34126102 Modeling hypoxia facilitates cancer cell survival through downregulation of p53 expression. 2021 Aug 25 1
4 31897141 β-elemene enhances cisplatin-induced apoptosis in bladder cancer cells through the ROS-AMPK signaling pathway. 2020 Jan 1
5 32020220 Suppression of DRP1‑mediated mitophagy increases the apoptosis of hepatocellular carcinoma cells in the setting of chemotherapy. 2020 Mar 1
6 32047579 Chlorella sorokiniana Extract Prevents Cisplatin-Induced Myelotoxicity In Vitro and In Vivo. 2020 1
7 32881246 Pioglitazone alleviates cisplatin nephrotoxicity by suppressing mitochondria-mediated apoptosis via SIRT1/p53 signalling. 2020 Oct 1
8 33202209 BNIP3 as a Regulator of Cisplatin-Induced Apoptosis. 2020 Oct 1
9 30867764 Efficacy of celastrol combined with cisplatin in enhancing the apoptosis of U-2OS osteosarcoma cells via the mitochondrial and endoplasmic reticulum pathways of apoptosis. 2019 Mar 1
10 31055231 Ellagic acid synergistically potentiates inhibitory activities of chemotherapeutic agents to human hepatocellular carcinoma. 2019 Jun 1
11 31661694 TRIAP1 Inhibition Activates the Cytochrome c/Apaf-1/Caspase-9 Signaling Pathway to Enhance Human Ovarian Cancer Sensitivity to Cisplatin. 2019 1
12 29434943 Mechanism of anticancer action of novel berenil complex of platinum(II) combined with anti-MUC1 in MCF-7 breast cancer cells. 2018 Feb 1
13 29467390 FGF1 induces resistance to chemotherapy in ovarian granulosa tumor cells through regulation of p53 mitochondrial localization. 2018 Feb 21 1
14 29523219 TIMP-3 Increases the Chemosensitivity of Laryngeal Carcinoma to Cisplatin via Facilitating Mitochondria-Dependent Apoptosis. 2018 Dec 27 1
15 30563166 Demethoxycurcumin-Loaded Chitosan Nanoparticle Downregulates DNA Repair Pathway to Improve Cisplatin-Induced Apoptosis in Non-Small Cell Lung Cancer. 2018 Dec 5 1
16 28214344 Neferine Potentiates the Antitumor Effect of Cisplatin in Human Lung Adenocarcinoma Cells Via a Mitochondria-Mediated Apoptosis Pathway. 2017 Sep 1
17 26925782 Reversal of cisplatin resistance by inhibiting PI3K/Akt signal pathway in human lung cancer cells. 2016 1
18 27751820 Inhibition of JNK and prothymosin-alpha sensitizes hepatocellular carcinoma cells to cisplatin. 2016 Dec 15 1
19 25567806 The X-ray structure of the primary adducts formed in the reaction between cisplatin and cytochrome c. 2015 Feb 14 2
20 25770930 Combination of chrysin and cisplatin promotes the apoptosis of Hep G2 cells by up-regulating p53. 2015 May 5 1
21 25796504 Cisplatin-mediated c-myc overexpression and cytochrome c (cyt c) release result in the up-regulation of the death receptors DR4 and DR5 and the activation of caspase 3 and caspase 9, likely responsible for the TRAIL-sensitizing effect of cisplatin. 2015 Apr 6
22 25894537 Loss of α(E)-catenin promotes Fas mediated apoptosis in tubular epithelial cells. 2015 Jul 1
23 26124336 Sulforaphene Synergistically Sensitizes Cisplatin via Enhanced Mitochondrial Dysfunction and PI3K/PTEN Modulation in Ovarian Cancer Cells. 2015 Jul 1
24 26338199 Carbon ion beam combined with cisplatin effectively disrupts triple negative breast cancer stem-like cells in vitro. 2015 Sep 4 1
25 26403741 [Overexpression of STOML-2 inhibits apoptosis of human cervical squamous carcinoma Siha cells in vitro]. 2015 Aug 2
26 24563380 Andrographolide sensitizes the cytotoxicity of human colorectal carcinoma cells toward cisplatin via enhancing apoptosis pathways in vitro and in vivo. 2014 May 1
27 24627125 β-elemene reverses the drug resistance of lung cancer A549/DDP cells via the mitochondrial apoptosis pathway. 2014 May 1
28 24854102 Inhibition of Beclin 1 expression enhances cisplatin-induced apoptosis through a mitochondrial-dependent pathway in human ovarian cancer SKOV3/DDP cells. 2014 1
29 25216531 Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma. 2014 Aug 30 1
30 22971517 Contrasting effects of α-tocopheryl succinate on cisplatin- and etoposide-induced apoptosis. 2013 Sep 1
31 23277286 Enhancement of cisplatin-induced apoptosis by β-elemene in resistant human ovarian cancer cells. 2013 Mar 1
32 23665025 Silencing of the STAT3 signaling pathway reverses the inherent and induced chemoresistance of human ovarian cancer cells. 2013 May 31 1
33 23720056 TR3 modulates platinum resistance in ovarian cancer. 2013 Aug 1 1
34 21798574 Overexpression of optic atrophy 1 protein increases cisplatin resistance via inactivation of caspase-dependent apoptosis in lung adenocarcinoma cells. 2012 Jan 1
35 22281241 Hsp70 promotes chemoresistance by blocking Bax mitochondrial translocation in ovarian cancer cells. 2012 Aug 28 1
36 22397496 Cisplatin resistance induced by decreased apoptotic activity in non-small-cell lung cancer cell lines. 2012 Mar 1 1
37 22746312 Probing the interaction of cisplatin with cytochrome C by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. 2012 Jul 17 5
38 21160028 Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis. 2011 Mar 1
39 21676925 Role of Smac in determining the chemotherapeutic response of esophageal squamous cell carcinoma. 2011 Aug 15 2
40 19889954 Inhibitors of histone deacetylases suppress cisplatin-induced p53 activation and apoptosis in renal tubular cells. 2010 Feb 1
41 20654585 Serine phosphorylation of glutathione S-transferase P1 (GSTP1) by PKCα enhances GSTP1-dependent cisplatin metabolism and resistance in human glioma cells. 2010 Nov 1 2
42 22545969 Evaluation of cisplatin in combination with β-elemene as a regimen for prostate cancer chemotherapy. 2010 Nov 1
43 19258036 Phospholipase A2-activating protein (PLAA) enhances cisplatin-induced apoptosis in HeLa cells. 2009 Jul 4
44 19276256 Enhancement of lexatumumab-induced apoptosis in human solid cancer cells by Cisplatin in caspase-dependent manner. 2009 Mar 15 1
45 19286393 Direct determination of the primary binding site of cisplatin on cytochrome C by mass spectrometry. 2009 Jun 6
46 19286655 Mismatch repair protein deficiency compromises cisplatin-induced apoptotic signaling. 2009 May 22 1
47 19351772 Valproate, in combination with pemetrexed and cisplatin, provides additional efficacy to the treatment of malignant mesothelioma. 2009 Apr 15 1
48 18214855 Calpain-mediated pathway dominates cisplatin-induced apoptosis in human lung adenocarcinoma cells as determined by real-time single cell analysis. 2008 May 15 2
49 18451495 Berberine, a natural product, combined with cisplatin enhanced apoptosis through a mitochondria/caspase-mediated pathway in HeLa cells. 2008 May 1
50 18606591 Participation of Omi Htra2 serine-protease activity in the apoptosis induced by cisplatin on SW480 colon cancer cells. 2008 Jun 1