Cisplatin

BCL2 like 1 ; Homo sapiens







109 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34907000 Senolytic-Mediated Elimination of Head and Neck Tumor Cells Induced Into Senescence by Cisplatin. 2022 Mar 1
2 32881195 Platycodin D suppresses cisplatin-induced cytotoxicity by suppressing ROS-mediated oxidative damage, apoptosis, and inflammation in HEK-293 cells. 2021 Jan 1
3 34088830 Therapeutic Synergy in Esophageal Cancer and Mesothelioma Is Predicted by Dynamic BH3 Profiling. 2021 Aug 1
4 34111459 Bcl-xL expression and regulation in the progression, recurrence, and cisplatin resistance of oral cancer. 2021 Sep 1 2
5 34322387 Downregulation of ATXN3 Enhances the Sensitivity to AKT Inhibitors (Perifosine or MK-2206), but Decreases the Sensitivity to Chemotherapeutic Drugs (Etoposide or Cisplatin) in Neuroblastoma Cells. 2021 1
6 31648572 Radiosensitizing Potential of Curcumin in Different Cancer Models. 2020 1
7 32945500 Inactivation of AKT/NF‑κB signaling by eurycomalactone decreases human NSCLC cell viability and improves the chemosensitivity to cisplatin. 2020 Oct 1
8 31262032 Trifluoperazine, an Antipsychotic Drug, Effectively Reduces Drug Resistance in Cisplatin-Resistant Urothelial Carcinoma Cells via Suppressing Bcl-xL: An In Vitro and In Vivo Study. 2019 Jun 30 3
9 31462500 Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer. 2019 Nov 2
10 31754340 RMP/URI inhibits both intrinsic and extrinsic apoptosis through different signaling pathways. 2019 1
11 29203930 Downregulation of liver-intestine cadherin enhances cisplatin-induced apoptosis in human gastric cancer BGC823 cells. 2018 Feb 1
12 29352235 Systems modeling accurately predicts responses to genotoxic agents and their synergism with BCL-2 inhibitors in triple negative breast cancer cells. 2018 Jan 19 1
13 30032449 Repression of GRIM19 expression potentiates cisplatin chemoresistance in advanced bladder cancer cells via disrupting ubiquitination-mediated Bcl-xL degradation. 2018 Oct 2
14 28597042 Cisplatin induces expression of drug resistance-related genes through c-jun N-terminal kinase pathway in human lung cancer cells. 2017 Aug 3
15 28617432 BST2 confers cisplatin resistance via NF-κB signaling in nasopharyngeal cancer. 2017 Jun 15 1
16 28963947 ABT737 induces mitochondrial pathway apoptosis and mitophagy by regulating DRP1-dependent mitochondrial fission in human ovarian cancer cells. 2017 Dec 1
17 28979680 Low concentration of chloroquine enhanced efficacy of cisplatin in the treatment of human ovarian cancer dependent on autophagy. 2017 1
18 29262633 Overexpression of miR-216b sensitizes NSCLC cells to cisplatin-induced apoptosis by targeting c-Jun. 2017 Nov 28 1
19 26860078 β-Catenin signaling pathway regulates cisplatin resistance in lung adenocarcinoma cells by upregulating Bcl-xl. 2016 Mar 2
20 27015836 Nrf2 inhibition sensitizes cholangiocarcinoma cells to cytotoxic and antiproliferative activities of chemotherapeutic agents. 2016 Aug 1
21 27127878 FXR agonists enhance the sensitivity of biliary tract cancer cells to cisplatin via SHP dependent inhibition of Bcl-xL expression. 2016 Jun 7 2
22 27226901 Cdk2 phosphorylation of Bcl-xL after stress converts it to a pro-apoptotic protein mimicking Bax/Bak. 2016 2
23 27494891 Analysis of the chemotherapeutic effects of a propadiene compound on malignant ovarian cancer cells. 2016 Aug 30 1
24 25310746 The alkaloid emetine sensitizes ovarian carcinoma cells to cisplatin through downregulation of bcl-xL. 2015 Jan 2
25 25992654 The Long Noncoding RNA MEG3 Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma. 2015 1
26 26201840 Antisense- and siRNA-mediated inhibition of the anti-apoptotic gene Bcl-xL for chemosensitization of bladder cancer cells. 2015 Sep 1
27 26239225 MicroRNA‑133a and microRNA‑326 co‑contribute to hepatocellular carcinoma 5‑fluorouracil and cisplatin sensitivity by directly targeting B‑cell lymphoma‑extra large. 2015 Oct 2
28 26497680 Mutant p53 confers chemoresistance in non-small cell lung cancer by upregulating Nrf2. 2015 Dec 8 2
29 26592553 MLN4924 Synergistically Enhances Cisplatin-induced Cytotoxicity via JNK and Bcl-xL Pathways in Human Urothelial Carcinoma. 2015 Nov 23 3
30 24286513 Protective effect of acetyl-l-carnitine against cisplatin ototoxicity: role of apoptosis-related genes and pro-inflammatory cytokines. 2014 Feb 1
31 24637722 CCN2 enhances resistance to cisplatin-mediating cell apoptosis in human osteosarcoma. 2014 2
32 23027129 RNA interference screening identifies a novel role for autocrine fibroblast growth factor signaling in neuroblastoma chemoresistance. 2013 Aug 22 1
33 23188704 Upregulation of the antiapoptotic factor Livin contributes to cisplatin resistance in colon cancer cells. 2013 Apr 1
34 23665025 Silencing of the STAT3 signaling pathway reverses the inherent and induced chemoresistance of human ovarian cancer cells. 2013 May 31 1
35 23912708 Combination of Ad-sTRAIL with the chemotherapeutic drug cisplatin synergistically enhances their pro-apoptotic ability in human breast cancer cells. 2013 Oct 1
36 23969971 Early responses of the STAT3 pathway to platinum drugs are associated with cisplatin resistance in epithelial ovarian cancer. 2013 Aug 1
37 24400442 Let-7c sensitizes acquired cisplatin-resistant A549 cells by targeting ABCC2 and Bcl-XL. 2013 Dec 1
38 22267549 Galiximab signals B-NHL cells and inhibits the activities of NF-κB-induced YY1- and snail-resistant factors: mechanism of sensitization to apoptosis by chemoimmunotherapeutic drugs. 2012 Mar 1
39 22431999 Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury. 2012 1
40 22445428 Cisplatin induces platelet apoptosis through the ERK signaling pathway. 2012 Jul 1
41 22983390 Migfilin sensitizes cisplatin-induced apoptosis in human glioma cells in vitro. 2012 Oct 1
42 21052098 Enhanced antitumor activity by combining an adenovirus harboring ING4 with cisplatin for hepatocarcinoma cells. 2011 Mar 1
43 21252285 Enhanced anticancer effect of the combination of cisplatin and TRAIL in triple-negative breast tumor cells. 2011 Mar 1
44 21863213 The p53 upregulated modulator of apoptosis (PUMA) chemosensitizes intrinsically resistant ovarian cancer cells to cisplatin by lowering the threshold set by Bcl-x(L) and Mcl-1. 2011 3
45 22033921 The microRNA 15a/16-1 cluster down-regulates protein repair isoaspartyl methyltransferase in hepatoma cells: implications for apoptosis regulation. 2011 Dec 23 1
46 19634140 Bcl-XL and MCL-1 constitute pertinent targets in ovarian carcinoma and their concomitant inhibition is sufficient to induce apoptosis. 2010 Feb 15 3
47 20142415 Downregulation of Bcl-xL and Mcl-1 is sufficient to induce cell death in mesothelioma cells highly refractory to conventional chemotherapy. 2010 Jun 2
48 20372863 ARL6IP1 mediates cisplatin-induced apoptosis in CaSki cervical cancer cells. 2010 May 3
49 20400521 The proapoptotic molecule BLID interacts with Bcl-XL and its downregulation in breast cancer correlates with poor disease-free and overall survival. 2010 Jun 1 1
50 20451370 Preclinical evidence for a beneficial impact of valproate on the response of small cell lung cancer to first-line chemotherapy. 2010 Jun 1