Berberine


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1417 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 insulin INS_HUMAN INS Homo sapiens 3630 7950 59
2 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 59
3 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 49
4 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 41
5 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 38
6 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 37
7 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 37
8 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 37
9 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 36
10 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 32
11 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 30
12 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 29
13 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 28
14 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 27
15 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 27
16 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 25
17 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 24
18 low density lipoprotein receptor LDLR_HUMAN LDLR Homo sapiens 3949 826 22
19 protein kinase AMP-activated catalytic subunit alpha 2 AAPK2_HUMAN PRKAA2 Homo sapiens 5563 919 22
20 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 20
21 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 20
22 protein kinase AMP-activated catalytic subunit alpha 1 AAPK1_HUMAN PRKAA1 Homo sapiens 5562 812 20
23 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 19
24 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 19
25 protein kinase AMP-activated catalytic subunit alpha 2 AAPK2_RAT Prkaa2 Rattus norvegicus 78975 753 19
26 interleukin 6 IL6_RAT Il6 Rattus norvegicus 24498 2269 19
27 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 18
28 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 18
29 BCL2, apoptosis regulator BCL2_RAT Bcl2 Rattus norvegicus 24224 1676 18
30 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 17
31 toll-like receptor 4 TLR4_RAT Tlr4 Rattus norvegicus 29260 826 17
32 transforming growth factor, beta 1 TGFB1_RAT Tgfb1 Rattus norvegicus 59086 1730 17
33 prostaglandin-endoperoxide synthase 2 PGH2_HUMAN PTGS2 Homo sapiens 5743 2572 17
34 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 17
35 acetylcholinesterase (Cartwright blood group) ACES_HUMAN ACHE Homo sapiens 43 3471 17
36 apolipoprotein E APOE_MOUSE Apoe Mus musculus 11816 1371 16
37 BCL2 associated X, apoptosis regulator G3V8T9_RAT Bax Rattus norvegicus 24887 1472 16
38 caspase 3 CASP3_MOUSE Casp3 Mus musculus 12367 1791 16
39 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 16
40 caspase 3 CASP3_RAT Casp3 Rattus norvegicus 25402 2178 15
41 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 15
42 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 14
43 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 14
44 sirtuin 1 SIR1_HUMAN SIRT1 Homo sapiens 23411 1253 14
45 proprotein convertase subtilisin/kexin type 9 PCSK9_HUMAN PCSK9 Homo sapiens 255738 518 14
46 interleukin 1 beta Q5BKB0_RAT Il1b Rattus norvegicus 24494 2252 14
47 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 13
48 NFE2 like bZIP transcription factor 2 NF2L2_RAT Nfe2l2 Rattus norvegicus 83619 1416 13
49 mitogen-activated protein kinase 8 MK08_MOUSE Mapk8 Mus musculus 26419 1537 13
50 mitogen-activated protein kinase 14 MK14_MOUSE Mapk14 Mus musculus 26416 2012 13