Protein Name interleukin 6
Organism Rattus norvegicus
Gene ID 24498
Gene Symbol


UniProt P20607 (IL6_RAT)
Relationships Total Number of functionally related compound(s) : 2269
Total Number of Articles : 4916

interleukin 6

Gene Summary

Enables cytokine activity and interleukin-6 receptor binding activity. Involved in several processes, including cellular response to lipid; positive regulation of cell communication; and response to peptide hormone. Located in cytoplasm and extracellular space. Used to study several diseases, including acute necrotizing pancreatitis; disseminated intravascular coagulation; fatty liver disease; hypertension (multiple); and impotence. Biomarker of several diseases, including acute necrotizing pancreatitis; artery disease (multiple); auditory system disease (multiple); iron deficiency anemia; and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and periodontal disease (multiple). Orthologous to human IL6 (interleukin 6). [provided by Alliance of Genome Resources, Apr 2022]

  • interleukin-6
  • IL-6
  • Interleukin 6 (interferon, beta 2)
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