Protein Name interleukin 6
Organism Mus musculus
Gene ID 16193
Gene Symbol


UniProt P08505 (IL6_MOUSE), A2RTD1 (A2RTD1_MOUSE), A0A0G2JGF4 (A0A0G2JGF4_MOUSE)
Relationships Total Number of functionally related compound(s) : 3985
Total Number of Articles : 8120

interleukin 6

Gene Summary

This gene encodes a member of the interleukin family of cytokines that have important functions in immune response, hematopoiesis, inflammation and the acute phase response. The ectopic overexpression of the encoded protein in mice results in excessive plasma cells in circulation, leading to death. Mice lacking the encoded protein exhibit abnormalities in hepatic acute phase response, some immune mechanisms, bone resorption in response to estrogen, liver regeneration and wound healing. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

  • interleukin-6
  • B-cell hybridoma growth factor
  • interleukin HP-1
Click to show/hide the synonyms