| Protein Name | BCL2 associated X, apoptosis regulator |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24887 |
| Gene Symbol | Bax |
| UniProt | G3V8T9 (G3V8T9_RAT), Q9JKL3 (Q9JKL3_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
1472
Total Number of Articles : 3067 |
Description |
BCL2 associated X, apoptosis regulator |
| Gene Summary |
Enables BH domain binding activity; heat shock protein binding activity; and protein-folding chaperone binding activity. Involved in several processes, including mitochondrion organization; regulation of apoptotic process; and response to anesthetic. Located in several cellular components, including cytosol; mitochondrial outer membrane; and perinuclear region of cytoplasm. Used to study brain glioma; endometriosis; morphine dependence; and pre-malignant neoplasm. Biomarker of several diseases, including artery disease (multiple); brain disease (multiple); heart disease (multiple); lung disease (multiple); and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; ataxia telangiectasia; colon adenocarcinoma; and colorectal cancer. Orthologous to human BAX (BCL2 associated X, apoptosis regulator). [provided by Alliance of Genome Resources, Jul 2025] |
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