Berberine

mechanistic target of rapamycin kinase ; Homo sapiens







27 Article(s)
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1 33130557 Berberine Represses β-Catenin Translation Involving 4E-BPs in Hepatocellular Carcinoma Cells. 2021 Jan 1
2 33417512 Berberine regulates the Notch1/PTEN/PI3K/AKT/mTOR pathway and acts synergistically with 17-AAG and SAHA in SW480 colon cancer cells. 2021 Dec 2
3 34643248 Berberine exerts its antineoplastic effects by reversing the Warburg effect via downregulation of the Akt/mTOR/GLUT1 signaling pathway. 2021 Dec 2
4 34981469 Evaluation of the Effects of Nanomicellar Curcumin, Berberine, and Their Combination with 5-Fluorouracil on Breast Cancer Cells. 2021 1
5 31926252 Berberine mitigates high glucose-induced podocyte apoptosis by modulating autophagy via the mTOR/P70S6K/4EBP1 pathway. 2020 Feb 15 3
6 32184626 Berberine Reverses Doxorubicin Resistance by Inhibiting Autophagy Through the PTEN/Akt/mTOR Signaling Pathway in Breast Cancer. 2020 2
7 32394178 Berberine Attenuates Cardiac Hypertrophy Through Inhibition of mTOR Signaling Pathway. 2020 Aug 2
8 32445451 AMPK and its Activator Berberine in the Treatment of Neurodegenerative Diseases. 2020 2
9 32454290 Berberine represses human gastric cancer cell growth in vitro and in vivo by inducing cytostatic autophagy via inhibition of MAPK/mTOR/p70S6K and Akt signaling pathways. 2020 Aug 4
10 32682817 Berberine and Emodin abrogates breast cancer growth and facilitates apoptosis through inactivation of SIK3-induced mTOR and Akt signaling pathway. 2020 Nov 1 2
11 32785222 The role of serum inflammatory cytokines and berberine in the insulin signaling pathway among women with polycystic ovary syndrome. 2020 3
12 33362566 Berberine Improves Chemo-Sensitivity to Cisplatin by Enhancing Cell Apoptosis and Repressing PI3K/AKT/mTOR Signaling Pathway in Gastric Cancer. 2020 3
13 33428132 Berberine Ameliorates Oxygen-glucose Deprivation/Reperfusion-induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress and Autophagy in PC12 Cells. 2020 Dec 3
14 31841506 Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively than did individual treatments. 2019 1
15 29537893 Inhibition of mTOR/S6K1/4E-BP1 Signaling by Nutraceutical SIRT1 Modulators. 2018 Apr 1
16 29565467 Berberine decelerates glucose metabolism via suppression of mTOR‑dependent HIF‑1α protein synthesis in colon cancer cells. 2018 May 5
17 30021340 Berberine promoted myocardial protection of postoperative patients through regulating myocardial autophagy. 2018 Sep 2
18 28063518 Role of nutraceutical SIRT1 modulators in AMPK and mTOR pathway: Evidence of a synergistic effect. 2017 Feb 1
19 29079630 ERK-dependent mTOR pathway is involved in berberine-induced autophagy in hepatic steatosis. 2017 Nov 1
20 27557493 Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway. 2016 Oct 11 1
21 25769560 Protective effect of Berberine pretreatment in hepatic ischemia/reperfusion injury of rat. 2015 Mar 2
22 25837881 Akt signaling is associated with the berberine-induced apoptosis of human gastric cancer cells. 2015 2
23 26722438 Berberine regulates proliferation, collagen synthesis and cytokine secretion of cardiac fibroblasts via AMPK-mTOR-p70S6K signaling pathway. 2015 4
24 24508518 Berberine improves pressure overload-induced cardiac hypertrophy and dysfunction through enhanced autophagy. 2014 Apr 5 2
25 25128467 FoxO proteins' nuclear retention and BH3-only protein Bim induction evoke mitochondrial dysfunction-mediated apoptosis in berberine-treated HepG2 cells. 2014 Nov 1
26 25310356 Berberine sensitizes rapamycin‑mediated human hepatoma cell death in vitro. 2014 Dec 6
27 20830746 Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism. 2010 Dec 15 2