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35217376 | Evaluation of the effects of natural isoquinoline alkaloids on low density lipoprotein receptor (LDLR) and proprotein convertase subtilisin/kexin type 9 (PCSK9) in hepatocytes, as new potential hypocholesterolemic agents. | 2022 Apr |
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34790723 | Berberine attenuates atherosclerotic lesions and hepatic steatosis in ApoE-/- mice by down-regulating PCSK9 via ERK1/2 pathway. | 2021 Oct |
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32001311 | Berberine in the treatment of metabolism-related chronic diseases: A drug cloud (dCloud) effect to target multifactorial disorders. | 2020 May |
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32789786 | Promising Anti-atherosclerotic Effect of Berberine: Evidence from In Vitro, In Vivo, and Clinical Studies. | 2020 |
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30335889 | Berberrubine and its analog, hydroxypropyl-berberrubine, regulate LDLR and PCSK9 expression via the ERK signal pathway to exert cholesterol-lowering effects in human hepatoma HepG2 cells. | 2018 Oct 18 |
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30563192 | Combination of Berberine with Resveratrol Improves the Lipid-Lowering Efficacy. | 2018 Dec 6 |
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27015087 | Genetic Variants of LDLR and PCSK9 Associated with Variations in Response to Antihypercholesterolemic Effects of Armolipid Plus with Berberine. | 2016 |
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26310319 | Effect of Berberine on promoting the excretion of cholesterol in high-fat diet-induced hyperlipidemic hamsters. | 2015 Aug 27 |
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24317011 | Ameliorative effect of Pracparatum mungo extract on high cholesterol diets in hamsters. | 2014 Jan |
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24321576 | Berberine metabolites could induce low density lipoprotein receptor up-regulation to exert lipid-lowering effects in human hepatoma cells. | 2014 Jan |
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23139291 | Upregulating reverse cholesterol transport with cholesteryl ester transfer protein inhibition requires combination with the LDL-lowering drug berberine in dyslipidemic hamsters. | 2013 Jan |
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23058107 | Synthesis and structure-activity relationship of berberine analogues in LDLR up-regulation and AMPK activation. | 2012 Nov 15 |
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19687008 | Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine. | 2009 Oct 16 |
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19800225 | Synthesis and biological evaluation of berberine analogues as novel up-regulators for both low-density-lipoprotein receptor and insulin receptor. | 2009 Nov 1 |
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18355829 | Berberine decreases PCSK9 expression in HepG2 cells. | 2008 Dec |
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18640378 | Combination of simvastatin with berberine improves the lipid-lowering efficacy. | 2008 Aug |
5 |
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18644725 | Synthesis and structure-activity relationships of berberine analogues as a novel class of low-density-lipoprotein receptor up-regulators. | 2008 Aug 15 |
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17767919 | Berberine-induced LDLR up-regulation involves JNK pathway. | 2007 Nov 3 |
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16508037 | Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine. | 2006 Jun |
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16890192 | Berberine inhibits 3T3-L1 adipocyte differentiation through the PPARgamma pathway. | 2006 Sep 22 |
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15926873 | Berberine--a novel approach to cholesterol lowering. | 2005 May |
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15531889 | Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. | 2004 Dec |
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