Berberine

caspase 3 ; Homo sapiens







49 Article(s)
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1 35085532 Involvement of environmentally relevant toxic metal mixture in Alzheimer's disease pathway alteration and protective role of berberine: Bioinformatics analysis and toxicogenomic screening. 2022 Mar 1
2 35571453 Berberine induces non-small cell lung cancer apoptosis via the activation of the ROS/ASK1/JNK pathway. 2022 Apr 1
3 33045871 Berberine modulates Keratin 17 to inhibit cervical cancer cell viability and metastasis. 2021 Dec 1
4 34258700 Hepatoprotective effects of phytochemicals berberine and umbelliferone against methotrexate-induced hepatic intoxication: experimental studies and in silico evidence. 2021 Dec 1
5 31688419 Berberine alleviates rotenone-induced cytotoxicity by antioxidation and activation of PI3K/Akt signaling pathway in SH-SY5Y cells. 2020 Jan 8 1
6 33011398 Effect of berberine associated with photodynamic therapy in cell lines. 2020 Dec 1
7 30396091 The impact of Keap1/Nrf2, P38MAPK/NF-κB and Bax/Bcl2/caspase-3 signaling pathways in the protective effects of berberine against methotrexate-induced nephrotoxicity. 2019 Jan 1
8 31052469 Synthesis and Anticancer Activity of Novel 9-O-Substituted Berberine Derivatives. 2019 May 1 1
9 31717305 C60 Fullerene as an Effective Nanoplatform of Alkaloid Berberine Delivery into Leukemic Cells. 2019 Nov 8 1
10 28679068 Berberine hydrochloride counteracts enhanced IL-8 expression induced by SN 38 in AGS cells. 2018 Aug 1
11 29260413 Berberine protects HK-2 cells from hypoxia/reoxygenation induced apoptosis via inhibiting SPHK1 expression. 2018 Mar 1
12 29564000 Berberine regulates the microRNA-21-ITGΒ4-PDCD4 axis and inhibits colon cancer viability. 2018 Apr 2
13 30006630 Cell-specific pattern of berberine pleiotropic effects on different human cell lines. 2018 Jul 13 2
14 28870132 Differential modes of photosensitisation in cancer cells by berberine and coralyne. 2017 Jul-Aug 1
15 28990249 Berberine inhibits the chemotherapy-induced repopulation by suppressing the arachidonic acid metabolic pathway and phosphorylation of FAK in ovarian cancer. 2017 Dec 1
16 29025293 Berberine Induces Apoptotic Cell Death via Activation of Caspase-3 and -8 in HL-60 Human Leukemia Cells: Nuclear Localization and Structure-Activity Relationships. 2017 1
17 27177238 Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis. 2016 Jul 1
18 27398330 Berberine Induced Apoptosis of Human Osteosarcoma Cells by Inhibiting Phosphoinositide 3 Kinase/Protein Kinase B (PI3K/Akt) Signal Pathway Activation. 2016 May 1
19 27995884 [Study of the effects in vitro of berberine combined with bortezomib on multiple myeloma cell line U266 cells]. 2016 Nov 14 1
20 25517919 Berberine induces apoptosis via ROS generation in PANC-1 and MIA-PaCa2 pancreatic cell lines. 2015 Feb 1
21 25837881 Akt signaling is associated with the berberine-induced apoptosis of human gastric cancer cells. 2015 1
22 26307103 Selective repression of RET proto-oncogene in medullary thyroid carcinoma by a natural alkaloid berberine. 2015 Aug 26 1
23 26503508 Berberine-induced anticancer activities in FaDu head and neck squamous cell carcinoma cells. 2015 Dec 1
24 24991192 Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation. 2014 1
25 25393968 Delayed luminescence to monitor programmed cell death induced by berberine on thyroid cancer cells. 2014 1
26 23784371 Berberine induces apoptosis via the mitochondrial pathway in liver cancer cells. 2013 Sep 1
27 23682426 Mechanisms involved in the cytotoxic effects of berberine on human colon cancer HCT-8 cells. 2012 Dec 2
28 21496227 Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells. 2011 Apr 15 1
29 21527846 Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells. 2011 Jul 1
30 21545798 Induction of G1 cell cycle arrest and apoptosis by berberine in bladder cancer cells. 2011 Jul 1 1
31 20930370 Berberine-induced apoptosis in human glioblastoma T98G cells is mediated by endoplasmic reticulum stress accompanying reactive oxygen species and mitochondrial dysfunction. 2010 1
32 24278513 Berberine inhibited radioresistant effects and enhanced anti-tumor effects in the irradiated-human prostate cancer cells. 2010 Jun 1
33 18459128 p53 Cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo. 2009 Jan 3
34 19360335 Berberine inhibits p53-dependent cell growth through induction of apoptosis of prostate cancer cells. 2009 May 1
35 19492307 The combination of berberine and irradiation enhances anti-cancer effects via activation of p38 MAPK pathway and ROS generation in human hepatoma cells. 2009 Aug 1 1
36 19652370 Berberine protects mesenchymal stem cells against hypoxia-induced apoptosis in vitro. 2009 Aug 1
37 19846952 Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells. 2009 Oct 2
38 18083161 Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-kappaB and Akt pathways. 2008 Feb 2 1
39 18379040 Berberine induces G1 arrest and apoptosis in human glioblastoma T98G cells through mitochondrial/caspases pathway. 2008 Apr 1
40 19189664 Berberine inhibits human neuroblastoma cell growth through induction of p53-dependent apoptosis. 2008 Nov-Dec 1
41 17673978 Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL. 2007 Oct 1
42 17970083 Berberine induces apoptosis in human HSC-3 oral cancer cells via simultaneous activation of the death receptor-mediated and mitochondrial pathway. 2007 Sep-Oct 2
43 17970084 GADD153 mediates berberine-induced apoptosis in human cervical cancer Ca ski cells. 2007 Sep-Oct 2
44 18001034 Protective effects of berberine against low-density lipoprotein (LDL) oxidation and oxidized LDL-induced cytotoxicity on endothelial cells. 2007 Dec 12 1
45 16440412 Berberine induces cell cycle arrest and apoptosis in human gastric carcinoma SNU-5 cell line. 2006 Jan 7 1
46 16475703 Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3. 2006 Jan-Feb 1
47 16505103 Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells. 2006 Feb 2
48 16610091 [Effects of berbamine on growth of leukemia cell line NB4 and its mechanism]. 2006 Mar 1
49 16621886 Berberine inhibits growth, induces G1 arrest and apoptosis in human epidermoid carcinoma A431 cells by regulating Cdki-Cdk-cyclin cascade, disruption of mitochondrial membrane potential and cleavage of caspase 3 and PARP. 2006 Oct 3