| 1 |
35217376 | Evaluation of the effects of natural isoquinoline alkaloids on low density lipoprotein receptor (LDLR) and proprotein convertase subtilisin/kexin type 9 (PCSK9) in hepatocytes, as new potential hypocholesterolemic agents. | 2022 Apr |
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| 2 |
34052738 | Structure-activity relationship and biological evaluation of berberine derivatives as PCSK9 down-regulating agents. | 2021 Aug |
3 |
| 3 |
34790723 | Berberine attenuates atherosclerotic lesions and hepatic steatosis in ApoE-/- mice by down-regulating PCSK9 via ERK1/2 pathway. | 2021 Oct |
2 |
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31812013 | Could PCSK9 be a new therapeutic target of Eugenol? In vitro and in silico evaluation of hypothesis. | 2020 Mar |
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| 5 |
31118464 | Regulation of Cholesterol Homeostasis by a Novel Long Non-coding RNA LASER. | 2019 May 22 |
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| 6 |
29294034 | Role of PCSK9 in the Development of Mouse Periodontitis Before and After Treatment: A Double-Edged Sword. | 2018 Jan 30 |
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29422010 | Berberine Encapsulated PLGA-PEG Nanoparticles Modulate PCSK-9 in HepG2 Cells. | 2018 |
3 |
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27015087 | Genetic Variants of LDLR and PCSK9 Associated with Variations in Response to Antihypercholesterolemic Effects of Armolipid Plus with Berberine. | 2016 |
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| 9 |
27754444 | The Potential Mechanisms of Berberine in the Treatment of Nonalcoholic Fatty Liver Disease. | 2016 Oct 14 |
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25540198 | Inhibition of PCSK9 transcription by berberine involves down-regulation of hepatic HNF1α protein expression through the ubiquitin-proteasome degradation pathway. | 2015 Feb 13 |
3 |
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22998978 | Nutraceutical pill containing berberine versus ezetimibe on plasma lipid pattern in hypercholesterolemic subjects and its additive effect in patients with familial hypercholesterolemia on stable cholesterol-lowering treatment. | 2012 Sep 22 |
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| 12 |
20623344 | The influence of PCSK9 polymorphisms on serum low-density lipoprotein cholesterol and risk of atherosclerosis. | 2010 Sep |
1 |
| 13 |
19687008 | Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine. | 2009 Oct 16 |
3 |
| 14 |
18355829 | Berberine decreases PCSK9 expression in HepG2 cells. | 2008 Dec |
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