Berberine

BCL2 apoptosis regulator ; Homo sapiens







37 Article(s)
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1 34942456 Integrating network pharmacology deciphers the action mechanism of Zuojin capsule in suppressing colorectal cancer. 2022 Feb 1
2 35085532 Involvement of environmentally relevant toxic metal mixture in Alzheimer's disease pathway alteration and protective role of berberine: Bioinformatics analysis and toxicogenomic screening. 2022 Mar 1
3 33045871 Berberine modulates Keratin 17 to inhibit cervical cancer cell viability and metastasis. 2021 Dec 1
4 33174291 Apoptotic effect of berberine via Bcl-2, ROR1, and mir-21 in patients with B-chronic lymphocytic leukemia. 2021 Apr 4
5 34258700 Hepatoprotective effects of phytochemicals berberine and umbelliferone against methotrexate-induced hepatic intoxication: experimental studies and in silico evidence. 2021 Dec 1
6 34943140 Alkaloid Escholidine and Its Interaction with DNA Structures. 2021 Nov 24 1
7 31399854 Berberine inhibits epithelial-mesenchymal transition and promotes apoptosis of tumour-associated fibroblast-induced colonic epithelial cells through regulation of TGF-β signalling. 2020 Mar 1
8 31688419 Berberine alleviates rotenone-induced cytotoxicity by antioxidation and activation of PI3K/Akt signaling pathway in SH-SY5Y cells. 2020 Jan 8 1
9 31743135 Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78. 2020 Feb 1
10 32272506 Berberine suppresses influenza virus-triggered NLRP3 inflammasome activation in macrophages by inducing mitophagy and decreasing mitochondrial ROS. 2020 Jul 2
11 33312221 Berberine Inhibits the Expression of SCT through miR-214-3p Stimulation in Breast Cancer Cells. 2020 1
12 30396091 The impact of Keap1/Nrf2, P38MAPK/NF-κB and Bax/Bcl2/caspase-3 signaling pathways in the protective effects of berberine against methotrexate-induced nephrotoxicity. 2019 Jan 1
13 30681073 Berberine Promotes Apoptosis of Colorectal Cancer via Regulation of the Long Non-Coding RNA (lncRNA) Cancer Susceptibility Candidate 2 (CASC2)/AU-Binding Factor 1 (AUF1)/B-Cell CLL/Lymphoma 2 (Bcl-2) Axis. 2019 Jan 25 4
14 31173223 Long non‑coding RNA CASC2 enhances berberine‑induced cytotoxicity in colorectal cancer cells by silencing BCL2. 2019 Aug 6
15 28679068 Berberine hydrochloride counteracts enhanced IL-8 expression induced by SN 38 in AGS cells. 2018 Aug 1
16 29260413 Berberine protects HK-2 cells from hypoxia/reoxygenation induced apoptosis via inhibiting SPHK1 expression. 2018 Mar 1
17 29732634 Berberine: Pathways to protect neurons. 2018 Aug 1
18 30272344 Berberine promotes nerve regeneration through IGFR‑mediated JNK‑AKT signal pathway. 2018 Dec 1
19 27177238 Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis. 2016 Jul 1
20 27398330 Berberine Induced Apoptosis of Human Osteosarcoma Cells by Inhibiting Phosphoinositide 3 Kinase/Protein Kinase B (PI3K/Akt) Signal Pathway Activation. 2016 May 1
21 27904693 Berberine upregulates miR-22-3p to suppress hepatocellular carcinoma cell proliferation by targeting Sp1. 2016 2
22 26400287 Inhibitory effect of berberine on human skin squamous cell carcinoma A431 cells. 2015 Sep 8 1
23 26503508 Berberine-induced anticancer activities in FaDu head and neck squamous cell carcinoma cells. 2015 Dec 1
24 23247593 Set9, NF-κB, and microRNA-21 mediate berberine-induced apoptosis of human multiple myeloma cells. 2013 Jan 2
25 22850597 Berberine inhibits growth and induces G1 arrest and apoptosis in human cholangiocarcinoma QBC939 cells. 2012 1
26 23682426 Mechanisms involved in the cytotoxic effects of berberine on human colon cancer HCT-8 cells. 2012 Dec 2
27 20656010 Cytotoxicity of berberine on human cervical carcinoma HeLa cells through mitochondria, death receptor and MAPK pathways, and in-silico drug-target prediction. 2010 Sep 1
28 20691179 Berberine induces apoptosis in breast cancer cells (MCF-7) through mitochondrial-dependent pathway. 2010 Oct 25 1
29 20930370 Berberine-induced apoptosis in human glioblastoma T98G cells is mediated by endoplasmic reticulum stress accompanying reactive oxygen species and mitochondrial dysfunction. 2010 1
30 24278513 Berberine inhibited radioresistant effects and enhanced anti-tumor effects in the irradiated-human prostate cancer cells. 2010 Jun 1
31 18459128 p53 Cooperates berberine-induced growth inhibition and apoptosis of non-small cell human lung cancer cells in vitro and tumor xenograft growth in vivo. 2009 Jan 1
32 19846952 Berberine induced apoptosis via promoting the expression of caspase-8, -9 and -3, apoptosis-inducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells. 2009 Oct 1
33 18379040 Berberine induces G1 arrest and apoptosis in human glioblastoma T98G cells through mitochondrial/caspases pathway. 2008 Apr 1
34 18451495 Berberine, a natural product, combined with cisplatin enhanced apoptosis through a mitochondria/caspase-mediated pathway in HeLa cells. 2008 May 1
35 17673978 Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL. 2007 Oct 1
36 17970084 GADD153 mediates berberine-induced apoptosis in human cervical cancer Ca ski cells. 2007 Sep-Oct 1
37 16505103 Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells. 2006 Feb 1