Berberine

mitogen-activated protein kinase 1 ; Homo sapiens







28 Article(s)
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1 34860319 Berberine increases the expression of cytokines and proteins linked to apoptosis in human melanoma cells. 2022 Mar 1
2 33959010 Berberine Regulated miR150-5p to Inhibit P2X7 Receptor, EMMPRIN and MMP-9 Expression in oxLDL Induced Macrophages. 2021 1
3 34358871 Berberine improves intestinal barrier function and reduces inflammation, immunosuppression, and oxidative stress by regulating the NF-κB/MAPK signaling pathway in deoxynivalenol-challenged piglets. 2021 Nov 15 1
4 32245183 Berberine Hampers Influenza A Replication through Inhibition of MAPK/ERK Pathway. 2020 Mar 21 1
5 32454290 Berberine represses human gastric cancer cell growth in vitro and in vivo by inducing cytostatic autophagy via inhibition of MAPK/mTOR/p70S6K and Akt signaling pathways. 2020 Aug 1
6 32969153 Immunomodulatory effects of berberine on the inflamed joint reveal new therapeutic targets for rheumatoid arthritis management. 2020 Nov 1
7 30343043 Antitumor effects of berberine against EGFR, ERK1/2, P38 and AKT in MDA-MB231 and MCF-7 breast cancer cells using molecular modelling and in vitro study. 2019 Feb 4
8 30502647 Inhibitory effect of berberine on interleukin-2 secretion from PHA-treated lymphocytic Jurkat cells. 2019 Jan 5
9 31781264 Berberine Modulates LPA Function to Inhibit the Proliferation and Inflammation of FLS-RA via p38/ERK MAPK Pathway Mediated by LPA1. 2019 6
10 29434321 The promotion function of Berberine for osteogenic differentiation of human periodontal ligament stem cells via ERK-FOS pathway mediated by EGFR. 2018 Feb 12 1
11 30061836 Berberine Improves Benign Prostatic Hyperplasia via Suppression of 5 Alpha Reductase and Extracellular Signal-Regulated Kinase in Vivo and in Vitro. 2018 1
12 30087941 Drug-Carrying Capacity and Anticancer Effect of the Folic Acid- and Berberine-Loaded Silver Nanomaterial To Regulate the AKT-ERK Pathway in Breast Cancer. 2018 Jul 31 1
13 30466991 Berberine down-regulates IL-8 expression through inhibition of the EGFR/MEK/ERK pathway in triple-negative breast cancer cells. 2018 Nov 15 1
14 31070539 Berberine inhibits angiogenesis in glioblastoma xenografts by targeting the VEGFR2/ERK pathway. 2018 Dec 3
15 29079630 ERK-dependent mTOR pathway is involved in berberine-induced autophagy in hepatic steatosis. 2017 Nov 1
16 26672764 Melatonin inhibits AP-2β/hTERT, NF-κB/COX-2 and Akt/ERK and activates caspase/Cyto C signaling to enhance the antitumor activity of berberine in lung cancer cells. 2016 Jan 19 3
17 27092498 Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine. 2016 Apr 16 1
18 26503508 Berberine-induced anticancer activities in FaDu head and neck squamous cell carcinoma cells. 2015 Dec 2
19 24905527 Berberine inhibits LPS-induced TF procoagulant activity and expression through NF-κB/p65, Akt and MAPK pathway in THP-1 cells. 2014 Jun 1
20 25493642 Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells. 2014 3
21 24184483 Berberine slows cell growth in autosomal dominant polycystic kidney disease cells. 2013 Nov 22 1
22 22120676 Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression. 2012 Feb 1 4
23 21527846 Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells. 2011 Jul 2
24 21738655 Berberine inhibits human hepatoma cell invasion without cytotoxicity in healthy hepatocytes. 2011 3
25 24278513 Berberine inhibited radioresistant effects and enhanced anti-tumor effects in the irradiated-human prostate cancer cells. 2010 Jun 1
26 17951041 Berberine inhibits TPA-induced MMP-9 and IL-6 expression in normal human keratinocytes. 2008 May 1
27 17767919 Berberine-induced LDLR up-regulation involves JNK pathway. 2007 Nov 3 1
28 16100034 Extracellular signal-regulated kinase-dependent stabilization of hepatic low-density lipoprotein receptor mRNA by herbal medicine berberine. 2005 Oct 1