Protein Name superoxide dismutase 2, mitochondrial
Organism Mus musculus
Gene ID 20656
Gene Symbol


UniProt P09671 (SODM_MOUSE), Q4FJX9 (Q4FJX9_MOUSE)
Relationships Total Number of functionally related compound(s) : 455
Total Number of Articles : 740

superoxide dismutase 2, mitochondrial

Gene Summary

Enables superoxide dismutase activity. Acts upstream of or within several processes, including animal organ development; apoptotic signaling pathway; and regulation of cellular biosynthetic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Used to study Canavan disease; Leigh disease; amyotrophic lateral sclerosis type 1; congestive heart failure; and dilated cardiomyopathy. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); lipid storage disease (multiple); liver disease (multiple); and optic nerve disease (multiple). Orthologous to human SOD2 (superoxide dismutase 2). [provided by Alliance of Genome Resources, Apr 2022]

  • superoxide dismutase [Mn], mitochondrial
  • manganese SOD
  • manganese superoxide dismutase
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