| 1 |
33841136 | Alternol Sensitizes Renal Carcinoma Cells to TRAIL-Induced Apoptosis. | 2021 |
3 |
| 2 |
33857626 | Sodium fluoride activates the extrinsic apoptosis via regulating NOX4/ROS-mediated p53/DR5 signaling pathway in lung cells both in vitro and in vivo. | 2021 Jun |
2 |
| 3 |
33937072 | LCT-3d Induces Oxidative Stress-Mediated Apoptosis by Upregulating Death Receptor 5 in Gastric Cancer Cells. | 2021 |
1 |
| 4 |
34479917 | Paclitaxel Impedes EGFR-mutated PC9 Cell Growth via Reactive Oxygen Species-mediated DNA Damage and EGFR/PI3K/AKT/mTOR Signaling Pathway Suppression. | 2021 Sep-Oct |
1 |
| 5 |
34582654 | Thymoquinone Crosstalks with DR5 to Sensitize TRAIL Resistance and Stimulate ROS-Mediated Cancer Apoptosis. | 2021 Sep 1 |
1 |
| 6 |
34599545 | CSC-3436 sensitizes triple negative breast cancer cells to TRAIL-induced apoptosis through ROS-mediated p38/CHOP/death receptor 5 signaling pathways. | 2021 Dec |
4 |
| 7 |
32124960 | Icariin sensitizes human colon cancer cells to TRAIL‑induced apoptosis via ERK‑mediated upregulation of death receptors. | 2020 Mar |
1 |
| 8 |
32506763 | ROS-mediated PERK-eIF2α-ATF4 pathway plays an important role in arsenite-induced L-02 cells apoptosis via regulating CHOP-DR5 signaling. | 2020 Oct |
2 |
| 9 |
33240775 | Curcumol Overcomes TRAIL Resistance of Non-Small Cell Lung Cancer by Targeting NRH:Quinone Oxidoreductase 2 (NQO2). | 2020 Nov |
1 |
| 10 |
30692634 | RUNX3 enhances TRAIL-induced apoptosis by upregulating DR5 in colorectal cancer. | 2019 May |
2 |
| 11 |
31019655 | Hsp90 Inhibitor SNX-2112 Enhances TRAIL-Induced Apoptosis of Human Cervical Cancer Cells via the ROS-Mediated JNK-p53-Autophagy-DR5 Pathway. | 2019 |
3 |
| 12 |
29535810 | Silibinin sensitizes TRAIL-mediated apoptosis by upregulating DR5 through ROS-induced endoplasmic reticulum stress-Ca2+-CaMKII-Sp1 pathway. | 2018 Feb 13 |
5 |
| 13 |
29800641 | Isoalantolactone induces apoptosis through reactive oxygen species-dependent upregulation of death receptor 5 in human esophageal cancer cells. | 2018 Aug 1 |
1 |
| 14 |
29964331 | Inhibition of euchromatin histone-lysine N-methyltransferase 2 sensitizes breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through reactive oxygen species-mediated activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway activation. | 2018 Nov |
3 |
| 15 |
30257253 | miR-128 Targets the SIRT1/ROS/DR5 Pathway to Sensitize Colorectal Cancer to TRAIL-Induced Apoptosis. | 2018 |
1 |
| 16 |
30359578 | C-27-carboxylated oleanane triterpenoids up-regulate TRAIL DISC assembly via p38 MAPK and CHOP-mediated DR5 expression in human glioblastoma cells. | 2018 Dec |
1 |
| 17 |
28209994 | Reversal of the Apoptotic Resistance of Non-Small-Cell Lung Carcinoma towards TRAIL by Natural Product Toosendanin. | 2017 Feb 17 |
2 |
| 18 |
28498435 | Plumbagin enhances TRAIL-induced apoptosis of human leukemic Kasumi‑1 cells through upregulation of TRAIL death receptor expression, activation of caspase-8 and inhibition of cFLIP. | 2017 Jun |
2 |
| 19 |
29164887 | Pterostilbene Enhances TRAIL-Induced Apoptosis through the Induction of Death Receptors and Downregulation of Cell Survival Proteins in TRAIL-Resistance Triple Negative Breast Cancer Cells. | 2017 Dec 27 |
3 |
| 20 |
26661339 | Decursin enhances TRAIL-induced apoptosis through oxidative stress mediated- endoplasmic reticulum stress signalling in non-small cell lung cancers. | 2016 Mar |
1 |
| 21 |
27594528 | A new brominated chalcone derivative suppresses the growth of gastric cancer cells in vitro and in vivo involving ROS mediated up-regulation of DR5 and 4 expression and apoptosis. | 2016 Oct 15 |
1 |
| 22 |
26111475 | Upregulation of Death Receptor 5 and Production of Reactive Oxygen Species Mediate Sensitization of PC-3 Prostate Cancer Cells to TRAIL Induced Apoptosis by Vitisin A. | 2015 |
1 |
| 23 |
24213373 | Indomethacin sensitizes TRAIL-resistant melanoma cells to TRAIL-induced apoptosis through ROS-mediated upregulation of death receptor 5 and downregulation of survivin. | 2014 May |
3 |
| 24 |
24401154 | Sensitization of hepatocellular carcinoma cells to Apo2L/TRAIL by a novel Akt/NF-κB signalling inhibitor. | 2014 Jun |
2 |
| 25 |
24612139 | Quercetin enhances apoptotic effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in ovarian cancer cells through reactive oxygen species (ROS) mediated CCAAT enhancer-binding protein homologous protein (CHOP)-death receptor 5 pathway. | 2014 May |
3 |
| 26 |
24919794 | Quinazoline analog HMJ-30 inhibits angiogenesis: involvement of endothelial cell apoptosis through ROS-JNK-mediated death receptor 5 signaling. | 2014 Aug |
1 |
| 27 |
25017974 | CCT327 enhances TRAIL-induced apoptosis through the induction of death receptors and downregulation of cell survival proteins in TRAIL-resistant human leukemia cells. | 2014 Sep |
2 |
| 28 |
25461556 | Camptothecin sensitizes human hepatoma Hep3B cells to TRAIL-mediated apoptosis via ROS-dependent death receptor 5 upregulation with the involvement of MAPKs. | 2014 Nov |
3 |
| 29 |
22982206 | Verrucarin A sensitizes TRAIL-induced apoptosis via the upregulation of DR5 in an eIF2α/CHOP-dependent manner. | 2013 Feb |
1 |
| 30 |
23135489 | Casticin, a flavonoid, potentiates TRAIL-induced apoptosis through modulation of anti-apoptotic proteins and death receptor 5 in colon cancer cells. | 2013 Feb |
1 |
| 31 |
23536831 | Casticin potentiates TRAIL-induced apoptosis of gastric cancer cells through endoplasmic reticulum stress. | 2013 |
2 |
| 32 |
23700228 | An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins. | 2013 Oct |
2 |
| 33 |
23846485 | Curcumin enhances TRAIL-induced apoptosis of breast cancer cells by regulating apoptosis-related proteins. | 2013 Nov |
1 |
| 34 |
24078627 | Azadirone, a limonoid tetranortriterpene, induces death receptors and sensitizes human cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through a p53 protein-independent mechanism: evidence for the role of the ROS-ERK-CHOP-death receptor pathway. | 2013 Nov 8 |
1 |
| 35 |
21660448 | 5, 7-Dimethoxyflavone sensitizes TRAIL-induced apoptosis through DR5 upregulation in hepatocellular carcinoma cells. | 2012 Jan |
1 |
| 36 |
22158615 | Death receptors 4 and 5 activate Nox1 NADPH oxidase through riboflavin kinase to induce reactive oxygen species-mediated apoptotic cell death. | 2012 Jan 27 |
5 |
| 37 |
22328338 | The anti-obesity drug orlistat promotes sensitivity to TRAIL by two different pathways in hormone-refractory prostate cancer cells. | 2012 May |
3 |
| 38 |
22354145 | AW00179 potentiates TRAIL-mediated death of human lung cancer H1299 cells through ROS-JNK-c-Jun-mediated up-regulation of DR5 and down-regulation of anti-apoptotic molecules. | 2012 Oct |
2 |
| 39 |
22400995 | Isoobtusilactone A sensitizes human hepatoma Hep G2 cells to TRAIL-induced apoptosis via ROS and CHOP-mediated up-regulation of DR5. | 2012 Apr 4 |
2 |
| 40 |
22666346 | Dihydroartemisinin enhances Apo2L/TRAIL-mediated apoptosis in pancreatic cancer cells via ROS-mediated up-regulation of death receptor 5. | 2012 |
2 |
| 41 |
22681760 | Snake venom toxin from Vipera lebetina turanica induces apoptosis of colon cancer cells via upregulation of ROS- and JNK-mediated death receptor expression. | 2012 Jun 8 |
2 |
| 42 |
22922338 | Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors. | 2012 Nov 15 |
2 |
| 43 |
23007278 | Snake venom toxin from Vipera lebetina turanica sensitizes cancer cells to TRAIL through ROS- and JNK-mediated upregulation of death receptors and downregulation of survival proteins. | 2012 Dec |
2 |
| 44 |
21078664 | Nimbolide sensitizes human colon cancer cells to TRAIL through reactive oxygen species- and ERK-dependent up-regulation of death receptors, p53, and Bax. | 2011 Jan 14 |
1 |
| 45 |
21127198 | ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins. | 2011 Jan 15 |
2 |
| 46 |
21362627 | Lipid raft-dependent death receptor 5 (DR5) expression and activation are critical for ursodeoxycholic acid-induced apoptosis in gastric cancer cells. | 2011 May |
3 |
| 47 |
21483669 | HIV infection enhances TRAIL-induced cell death in macrophage by down-regulating decoy receptor expression and generation of reactive oxygen species. | 2011 Apr 5 |
2 |
| 48 |
21931821 | Resveratrol suppresses constitutive activation of AKT via generation of ROS and induces apoptosis in diffuse large B cell lymphoma cell lines. | 2011 |
1 |
| 49 |
21978492 | Coexpression of activated c-Met and death receptor 5 predicts better survival in colorectal carcinoma. | 2011 Dec |
1 |
| 50 |
20154087 | Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors. | 2010 Apr 9 |
1 |