Reactive Oxygen Species

caspase 9 ; Homo sapiens







63 Article(s)
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1 34110565 Silica Nanoparticles Induce Hepatotoxicity by Triggering Oxidative Damage, Apoptosis, and Bax-Bcl2 Signaling Pathway. 2022 Apr 1
2 34674796 Pulsed electromagnetic field potentiates etoposide-induced MCF-7 cell death. 2022 Mar 1
3 34989943 A novel antagonist of TRPM2 and TRPV4 channels: Carvacrol. 2022 Mar 2
4 35002403 A possible theranostic approach of chitosan-coated iron oxide nanoparticles against human colorectal carcinoma (HCT-116) cell line. 2022 Jan 2
5 35202708 Carbon tetrachloride induced mitochondrial division, respiratory chain damage, abnormal intracellular [H+] and apoptosis are due to the activation of 5-HT degradation system in hepatocytes. 2022 Mar 15 2
6 32573644 Fruiting body polysaccharides of Hericium erinaceus induce apoptosis in human colorectal cancer cells via ROS generation mediating caspase-9-dependent signaling pathways. 2020 Jul 22 1
7 32715490 Cytotoxic activity of dimeric acridone alkaloids derived from Citrus plants towards human leukaemia HL-60 cells. 2020 Oct 1
8 30159798 Inhibitions of anandamide transport and FAAH synthesis decrease apoptosis and oxidative stress through inhibition of TRPV1 channel in an in vitro seizure model. 2019 Mar 2
9 30365122 Vorinostat enhances gefitinib‑induced cell death through reactive oxygen species‑dependent cleavage of HSP90 and its clients in non‑small cell lung cancer with the EGFR mutation. 2019 Jan 2
10 30408460 A synthetic chalcone derivative, 2-hydroxy-3',5,5'-trimethoxychalcone (DK-139), triggers reactive oxygen species-induced apoptosis independently of p53 in A549 lung cancer cells. 2019 Jan 25 1
11 30542709 Apoptosis induced by ursodeoxycholic acid in human melanoma cells through the mitochondrial pathway. 2019 Jan 1
12 31091501 Spermatogenesis disorder caused by T-2 toxin is associated with germ cell apoptosis mediated by oxidative stress. 2019 Aug 1
13 31389193 Cell Membrane-Coated Magnetic Nanocubes with a Homotypic Targeting Ability Increase Intracellular Temperature due to ROS Scavenging and Act as a Versatile Theranostic System for Glioblastoma Multiforme. 2019 Sep 1
14 31663577 Fenton-reaction-stimulative nanoparticles decorated with a reactive-oxygen-species (ROS)-responsive molecular switch for ROS amplification and triple negative breast cancer therapy. 2019 Dec 7 1
15 29475060 Lanatoside C inhibits cell proliferation and induces apoptosis through attenuating Wnt/β-catenin/c-Myc signaling pathway in human gastric cancer cell. 2018 Apr 2
16 29658330 Comparative cytotoxicity and apoptotic pathways induced by nanosilver in human liver HepG2 and L02 cells. 2018 Dec 1
17 29915539 Mitochondrial Delivery of Phenol Substructure Triggers Mitochondrial Depolarization and Apoptosis of Cancer Cells. 2018 1
18 29958912 Selective self-induced stimulus amplification prodrug platform for inhibiting multidrug resistance and lung metastasis. 2018 Aug 28 1
19 30204479 Bixin Triggers Apoptosis of Human Hep3B Hepatocellular Carcinoma Cells: An Insight to Molecular and IN SILICO Approach. 2018 Aug-Sep 1
20 28123590 Bovine lactoferricin P13 triggers ROS-mediated caspase-dependent apoptosis in SMMC7721 cells. 2017 Jan 2
21 28239299 Synthetic curcumin derivative DK1 possessed G2/M arrest and induced apoptosis through accumulation of intracellular ROS in MCF-7 breast cancer cells. 2017 1
22 28548942 The N-terminal tail coordinates with carbohydrate recognition domain to mediate galectin-3 induced apoptosis in T cells. 2017 Jul 25 2
23 28717222 FTY720 Induces Autophagy-Associated Apoptosis in Human Oral Squamous Carcinoma Cells, in Part, through a Reactive Oxygen Species/Mcl-1-Dependent Mechanism. 2017 Jul 17 1
24 29110583 Beta-mangostin from Cratoxylum arborescens activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G0/G1 cell-cycle arrest. 2017 Nov 1
25 27594528 A new brominated chalcone derivative suppresses the growth of gastric cancer cells in vitro and in vivo involving ROS mediated up-regulation of DR5 and 4 expression and apoptosis. 2016 Oct 15 1
26 25673508 Multiple protective mechanisms of alpha-lipoic acid in oxidation, apoptosis and inflammation against hydrogen peroxide induced toxicity in human lymphocytes. 2015 May 1
27 25800307 The protein l-isoaspartyl (d-aspartyl) methyltransferase protects against dopamine-induced apoptosis in neuroblastoma SH-SY5Y cells. 2015 Jun 4 1
28 25912482 Insights into the importance for designing curcumin-inspired anticancer agents by a prooxidant strategy: The case of diarylpentanoids. 2015 Aug 1
29 26648189 Inhibition of caspase-9 by oridonin, a diterpenoid isolated from Rabdosia rubescens, augments apoptosis in human laryngeal cancer cells. 2015 Dec 4
30 24551054 Subditine, a new monoterpenoid indole alkaloid from bark of Nauclea subdita (Korth.) Steud. induces apoptosis in human prostate cancer cells. 2014 1
31 24927175 Tazarotene induces apoptosis in human basal cell carcinoma via activation of caspase-8/t-Bid and the reactive oxygen species-dependent mitochondrial pathway. 2014 Oct 3
32 23122111 Neferine induces reactive oxygen species mediated intrinsic pathway of apoptosis in HepG2 cells. 2013 Jan 15 1
33 23660334 Sanguinarine induces apoptosis in human colorectal cancer HCT-116 cells through ROS-mediated Egr-1 activation and mitochondrial dysfunction. 2013 Jul 4 1
34 23661289 Artemisinin induces A549 cell apoptosis dominantly via a reactive oxygen species-mediated amplification activation loop among caspase-9, -8 and -3. 2013 Oct 3
35 23685456 ROS and ERK1/2-mediated caspase-9 activation increases XAF1 expression in dexamethasone-induced apoptosis of EBV-transformed B cells. 2013 Jul 1
36 22368256 The role of p53 in an apoptotic process caused by an oral malodorous compound in periodontal tissues: a review. 2012 Mar 2
37 22565279 Anti-benzopyrene-7,8-diol-9,10-epoxide induces apoptosis via mitochondrial pathway in human bronchiolar epithelium cells independent of the mitochondria permeability transition pore. 2012 Jul 1
38 21041304 Regulator of G protein signaling 6 (RGS6) induces apoptosis via a mitochondrial-dependent pathway not involving its GTPase-activating protein activity. 2011 Jan 14 1
39 19889614 Daidzein induces MCF-7 breast cancer cell apoptosis via the mitochondrial pathway. 2010 Feb 1
40 19238172 Oxidative modification of caspase-9 facilitates its activation via disulfide-mediated interaction with Apaf-1. 2009 Apr 3
41 19292871 Chronic high-dose morphine treatment promotes SH-SY5Y cell apoptosis via c-Jun N-terminal kinase-mediated activation of mitochondria-dependent pathway. 2009 Apr 1
42 20187293 Reactive oxygen species and p38 mitogen-activated protein kinase induce apoptotic death of U937 cells in response to Naja nigricollis toxin-gamma. 2009 Aug 1
43 17985347 Reactive oxygen species-dependent destruction of MEK and Akt in Manumycin stimulated death of lymphoid tumor and myeloma cell lines. 2008 Apr 1 2
44 16968671 Activation of mitochondrial-driven apoptosis in skeletal muscle cells is not mediated by reactive oxygen species production. 2007 1
45 17145774 Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death. 2007 Feb 1
46 17309078 Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells. 2007 May 1
47 17904098 Hypoxia/reoxygenation induces apoptosis through a ROS-mediated caspase-8/Bid/Bax pathway in human lymphocytes. 2007 Nov 23 1
48 16990509 Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation. 2006 Dec 1
49 16007191 Caspase-9 and effector caspases have sequential and distinct effects on mitochondria. 2005 Sep 22 4
50 16103097 Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines. 2005 Aug 15 1