CPRiL

Protein Name	mitogen activated protein kinase 14
Organism	Rattus norvegicus
Gene ID	81649
Gene Symbol	Mapk14
UniProt	Q56A33 (Q56A33_RAT), G3V617 (G3V617_RAT)
Relationships	Total Number of functionally related compound(s) : 1429 Total Number of Articles : 2722
Description	mitogen activated protein kinase 14
Gene Summary	Enables ATP binding activity and MAP kinase activity. Involved in several processes, including cellular response to acetaldehyde; cellular response to transforming growth factor beta stimulus; and stress-activated MAPK cascade. Predicted to be located in mitochondrion; nuclear speck; and spindle pole. Predicted to be active in cytosol; glutamatergic synapse; and nucleus. Used to study diabetic neuropathy and osteoporosis. Biomarker of Alzheimer's disease; anti-basement membrane glomerulonephritis; and interstitial cystitis. Human ortholog(s) of this gene implicated in colon cancer; colorectal carcinoma; nasopharynx carcinoma; and rectum cancer. Orthologous to human MAPK14 (mitogen-activated protein kinase 14). [provided by Alliance of Genome Resources, Jul 2025]
synonyms	mitogen-activated protein kinase 14 Csaids binding protein MAP kinase 14 MAP kinase 2 MAP kinase Mxi2 MAP kinase p38 alpha MAPK 14 MAX-interacting protein 2 cytokine suppressive anti-inflammatory drug binding protein cytokine-supressive anti-inflammatory drug binding protein mitogen-activated protein kinase 14A mitogen-activated protein kinase p38 alpha p38 MAP kinase p38 mitogen activated protein kinase p38alpha Exip reactive kinase stress-activated protein kinase 2A CRK1 CSBP CSPB1 Csbp1 Csbp2 Exip Hog Mxi2 Prkm14 Prkm15 RK Sapk2A p38 Click to show/hide the synonyms
Properties