Protein Name nitric oxide synthase 2
Organism Homo sapiens
Gene ID 4843
Gene Symbol

NOS2

UniProt P35228 (NOS2_HUMAN)
Relationships Total Number of functionally related compound(s) : 2012
Total Number of Articles : 4387
Description

nitric oxide synthase 2

Gene Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

synonyms
  • nitric oxide synthase, inducible
  • NOS, type II
  • hepatocyte NOS
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Properties