Reactive Oxygen Species

DNA damage inducible transcript 3 ; Homo sapiens







80 Article(s)
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1 34993544 Generation of endoplasmic reticulum stress-dependent reactive oxygen species mediates TGF-β1-induced podocyte migration. 2022 Mar 3 1
2 35151835 Glaucocalyxin A impairs tumor growth via amplification of the ATF4/CHOP/CHAC1 cascade in human oral squamous cell carcinoma. 2022 May 23 1
3 35427876 Perfluorooctanoic acid exposure increases both proliferation and apoptosis of human placental trophoblast cells mediated by ER stress-induced ROS or UPR pathways. 2022 May 1 1
4 34054558 In vitro Anticancer Effects of JI017 on Two Prostate Cancer Cell Lines Involve Endoplasmic Reticulum Stress Mediated by Elevated Levels of Reactive Oxygen Species. 2021 2
5 34599545 CSC-3436 sensitizes triple negative breast cancer cells to TRAIL-induced apoptosis through ROS-mediated p38/CHOP/death receptor 5 signaling pathways. 2021 Dec 3
6 32506763 ROS-mediated PERK-eIF2α-ATF4 pathway plays an important role in arsenite-induced L-02 cells apoptosis via regulating CHOP-DR5 signaling. 2020 Oct 2
7 32604833 TRPV1 Antagonist DWP05195 Induces ER Stress-Dependent Apoptosis through the ROS-p38-CHOP Pathway in Human Ovarian Cancer Cells. 2020 Jun 26 1
8 32700751 Sensitivity of allyl isothiocyanate to induce apoptosis via ER stress and the mitochondrial pathway upon ROS production in colorectal adenocarcinoma cells. 2020 Oct 2
9 32878253 Interactions of Zinc Oxide Nanostructures with Mammalian Cells: Cytotoxicity and Photocatalytic Toxicity. 2020 Aug 31 2
10 33042407 Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux. 2020 1
11 30692634 RUNX3 enhances TRAIL-induced apoptosis by upregulating DR5 in colorectal cancer. 2019 May 2
12 30798142 Luteolin, a flavonoid, as an anticancer agent: A review. 2019 Apr 2
13 30871017 Pleiotropic Pharmacological Actions of Capsazepine, a Synthetic Analogue of Capsaicin, against Various Cancers and Inflammatory Diseases. 2019 Mar 12 1
14 31054874 Endoplasmic reticulum stress and autophagy contribute to cadmium-induced cytotoxicity in retinal pigment epithelial cells. 2019 Sep 1 1
15 31360107 PERK/eIF-2α/CHOP Pathway Dependent ROS Generation Mediates Butein-induced Non-small-cell Lung Cancer Apoptosis and G2/M Phase Arrest. 2019 1
16 29167125 Mesenchymal stem cells reduce hypoxia-induced apoptosis in alveolar epithelial cells by modulating HIF and ROS hypoxic signaling. 2018 Mar 1 1
17 29328423 Cetuximab enhances cisplatin-induced endoplasmic reticulum stress-associated apoptosis in laryngeal squamous cell carcinoma cells by inhibiting expression of TXNDC5. 2018 Mar 1
18 29433671 Phytochemical-induced reactive oxygen species and endoplasmic reticulum stress-mediated apoptosis and differentiation in malignant melanoma cells. 2018 Jan 15 2
19 29964331 Inhibition of euchromatin histone-lysine N-methyltransferase 2 sensitizes breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through reactive oxygen species-mediated activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway activation. 2018 Nov 3
20 30300626 Chrysophanol selectively represses breast cancer cell growth by inducing reactive oxygen species production and endoplasmic reticulum stress via AKT and mitogen-activated protein kinase signal pathways. 2018 Dec 1 2
21 28282786 Galangin potentiates human breast cancer to apoptosis induced by TRAIL through activating AMPK. 2017 May 2
22 28323103 Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway. 2017 Jun 2
23 28402965 Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway. 2017 Jun 20 3
24 28412728 Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells. 2017 Apr 18 1
25 28573788 In vitro additive antitumor effects of dimethoxycurcumin and 5-fluorouracil in colon cancer cells. 2017 Jul 1
26 28630460 Oxidative and endoplasmic reticulum stress is impaired in leukocytes from metabolically unhealthy vs healthy obese individuals. 2017 Oct 1
27 28642847 Heat-Labile Enterotoxin-Induced PERK-CHOP Pathway Activation Causes Intestinal Epithelial Cell Apoptosis. 2017 3
28 28668332 Ethanol-induced PGE2 up-regulates Aβ production through PKA/CREB signaling pathway. 2017 Nov 2
29 29164887 Pterostilbene Enhances TRAIL-Induced Apoptosis through the Induction of Death Receptors and Downregulation of Cell Survival Proteins in TRAIL-Resistance Triple Negative Breast Cancer Cells. 2017 Dec 27 1
30 26847145 Licochalcone B induces apoptosis of human oral squamous cell carcinoma through the extrinsic- and intrinsic-signaling pathways. 2016 Apr 2
31 27262990 Three components of cigarette smoke altered the growth and apoptosis of metastatic colon cancer cells via inducing the synthesis of reactive oxygen species and endoplasmic reticulum stress. 2016 Jul 2
32 27432061 Echinacoside Protects Against MPP(+)-Induced Neuronal Apoptosis via ROS/ATF3/CHOP Pathway Regulation. 2016 Aug 2
33 27573888 Non-thermal gas plasma-induced endoplasmic reticulum stress mediates apoptosis in human colon cancer cells. 2016 Oct 2
34 27634458 Endoplasmic reticulum stress-mediated neuronal apoptosis by acrylamide exposure. 2016 Nov 1 1
35 27895312 Activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway in human lung cancer cells by the new synthetic flavonoid, LZ-205. 2016 Dec 27 2
36 25788268 Piperlongumine selectively kills hepatocellular carcinoma cells and preferentially inhibits their invasion via ROS-ER-MAPKs-CHOP. 2015 Mar 20 1
37 25872712 Sodium fluoride induces apoptosis through reactive oxygen species-mediated endoplasmic reticulum stress pathway in Sertoli cells. 2015 Apr 1 1
38 26009870 Glycyrrhizic acid (GA) inhibits reactive oxygen Species mediated photodamage by blocking ER stress and MAPK pathway in UV-B irradiated human skin fibroblasts. 2015 Jul 1
39 26284193 ROS Accumulation by PEITC Selectively Kills Ovarian Cancer Cells via UPR-Mediated Apoptosis. 2015 4
40 24213373 Indomethacin sensitizes TRAIL-resistant melanoma cells to TRAIL-induced apoptosis through ROS-mediated upregulation of death receptor 5 and downregulation of survivin. 2014 May 2
41 24525405 Valproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells. 2014 Apr 2
42 24551210 Ampelopsin induces cell growth inhibition and apoptosis in breast cancer cells through ROS generation and endoplasmic reticulum stress pathway. 2014 1
43 24612139 Quercetin enhances apoptotic effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in ovarian cancer cells through reactive oxygen species (ROS) mediated CCAAT enhancer-binding protein homologous protein (CHOP)-death receptor 5 pathway. 2014 May 6
44 25023940 Piperlongumine induces cell death through ROS-mediated CHOP activation and potentiates TRAIL-induced cell death in breast cancer cells. 2014 Dec 6
45 25104093 The effects and underlying mechanism of excessive iodide on excessive fluoride-induced thyroid cytotoxicity. 2014 Jul 1
46 25412307 Activation of volume-sensitive outwardly rectifying chloride channel by ROS contributes to ER stress and cardiac contractile dysfunction: involvement of CHOP through Wnt. 2014 Nov 20 1
47 22676837 Crosstalk between endoplasmic reticulum stress and oxidative stress in apoptosis induced by α-tocopheryl succinate in human gastric carcinoma cells. 2013 Feb 28 1
48 22982206 Verrucarin A sensitizes TRAIL-induced apoptosis via the upregulation of DR5 in an eIF2α/CHOP-dependent manner. 2013 Feb 1
49 23333652 Trans-10, cis-12 conjugated linoleic acid induced cell death in human colon cancer cells through reactive oxygen species-mediated ER stress. 2013 Apr 1
50 23339468 Cadmium induces neuronal cell death through reactive oxygen species activated by GADD153. 2013 Jan 22 3