| 1 |
35074639 | A novel multifunctional nanoparticles formed by molecular recognition between AS1411 aptamer and redox-responsive paclitaxel-nucleoside analogue prodrug for combination treatment of β-lapachone and paclitaxel. | 2022 Apr |
4 |
| 2 |
35245730 | Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy. | 2022 Apr |
1 |
| 3 |
35434015 | Nrf2 protects against cerebral ischemia-reperfusion injury by suppressing programmed necrosis and inflammatory signaling pathways. | 2022 Mar |
2 |
| 4 |
35618186 | Bladder cancer selective chemotherapy with potent NQO1 substrate co-loaded prodrug nanoparticles. | 2022 May 31 |
4 |
| 5 |
33316526 | Activation of the ROS/HO-1/NQO1 signaling pathway contributes to the copper-induced oxidative stress and autophagy in duck renal tubular epithelial cells. | 2021 Feb 25 |
2 |
| 6 |
33576220 | Enzyme-Triggered Disassembly of Polymeric Micelles by Controlled Depolymerization via Cascade Cyclization for Anticancer Drug Delivery. | 2021 Feb 24 |
4 |
| 7 |
33652166 | DT-diaphorase triggered theranostic nanoparticles induce the self-burst of reactive oxygen species for tumor diagnosis and treatment. | 2021 Apr 15 |
2 |
| 8 |
34083537 | STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer. | 2021 Jun 3 |
1 |
| 9 |
34091287 | Transforming iodoquinol into broad spectrum anti-tumor leads: Repurposing to modulate redox homeostasis. | 2021 Aug |
1 |
| 10 |
34291369 | Phase I study of napabucasin in combination with FOLFIRI + bevacizumab in Japanese patients with metastatic colorectal cancer. | 2021 Nov |
1 |
| 11 |
34439319 | Measuring NQO1 Bioactivation Using [2H7]Glucose. | 2021 Aug 19 |
4 |
| 12 |
34691356 | Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells. | 2021 |
2 |
| 13 |
34747277 | ROS-Activated homodimeric podophyllotoxin nanomedicine with self-accelerating drug release for efficient cancer eradication. | 2021 Dec |
2 |
| 14 |
32021165 | A pH-Responsive Charge-Reversal Drug Delivery System with Tumor-Specific Drug Release and ROS Generation for Cancer Therapy. | 2020 |
2 |
| 15 |
32645959 | Insights into the New Cancer Therapy through Redox Homeostasis and Metabolic Shifts. | 2020 Jul 7 |
1 |
| 16 |
32706272 | A pH/ROS cascade-responsive and self-accelerating drug release nanosystem for the targeted treatment of multi-drug-resistant colon cancer. | 2020 Dec |
1 |
| 17 |
32739527 | NADPH-quinone oxidoreductase-1 mediates Benzo-[a]-pyrene-1,6-quinone-induced cytotoxicity and reactive oxygen species production in human EA.hy926 endothelial cells. | 2020 Oct 1 |
3 |
| 18 |
32801467 | Enzymatically synthesized glycogen prevents ultraviolet B-induced cell damage in normal human epidermal keratinocytes. | 2020 Jul |
1 |
| 19 |
33087132 | Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma. | 2020 Oct 21 |
2 |
| 20 |
30612064 | Integrated block copolymer prodrug nanoparticles for combination of tumor oxidative stress amplification and ROS-responsive drug release. | 2019 Mar |
2 |
| 21 |
30737573 | Combination treatment with highly bioavailable curcumin and NQO1 inhibitor exhibits potent antitumor effects on esophageal squamous cell carcinoma. | 2019 Aug |
1 |
| 22 |
30758914 | Protective effects of α-lipoic acid on cultured human nasal fibroblasts exposed to urban particulate matter. | 2019 Jun |
1 |
| 23 |
30776144 | Possible association of HMOX1 and NQO1 polymorphisms with anti-tuberculosis drug-induced liver injury: A matched case-control study. | 2019 Aug |
1 |
| 24 |
30828537 | A pH/ROS Cascade-Responsive Charge-Reversal Nanosystem with Self-Amplified Drug Release for Synergistic Oxidation-Chemotherapy. | 2019 Feb 20 |
2 |
| 25 |
31322268 | Protein kinase A activation by β‑Lapachone is associated with apoptotic cell death in NQO1‑overexpressing breast cancer cells. | 2019 Oct |
2 |
| 26 |
31360690 | Ajoene, a Major Organosulfide Found in Crushed Garlic, Induces NAD(P)H:quinone Oxidoreductase Expression Through Nuclear Factor E2-related Factor-2 Activation in Human Breast Epithelial Cells. | 2019 Jun |
2 |
| 27 |
31470592 | Nutritional Stress in Head and Neck Cancer Originating Cell Lines: The Sensitivity of the NRF2-NQO1 Axis. | 2019 Aug 29 |
1 |
| 28 |
31527169 | Bioactivation of Napabucasin Triggers Reactive Oxygen Species-Mediated Cancer Cell Death. | 2019 Dec 1 |
3 |
| 29 |
31664812 | Enzyme-Catalytic Self-Triggered Release of Drugs from a Nanosystem for Efficient Delivery to Nuclei of Tumor Cells. | 2019 Nov 20 |
4 |
| 30 |
29108775 | Facilitation of 9,10-phenanthrenequinone-elicited neuroblastoma cell apoptosis by NAD(P)H:quinone oxidoreductase 1. | 2018 Jan 5 |
2 |
| 31 |
29294389 | NQO1 downregulation potentiates menadione-induced endothelial-mesenchymal transition during rosette formation in Fuchs endothelial corneal dystrophy. | 2018 Feb 20 |
1 |
| 32 |
29582209 | Long-term exposure to TNF-α leads human skin fibroblasts to a p38 MAPK- and ROS-mediated premature senescence. | 2018 Jul |
1 |
| 33 |
30595797 | NQO1 Is Regulated by PTEN in Glioblastoma, Mediating Cell Proliferation and Oxidative Stress. | 2018 |
5 |
| 34 |
27975234 | Pharmacokinetics and derivation of an anticancer dosing regimen for the novel anti-cancer agent isobutyl-deoxynyboquinone (IB-DNQ), a NQO1 bioactivatable molecule, in the domestic felid species. | 2017 Apr |
1 |
| 35 |
28639725 | Targeting NAD(P)H:Quinone Oxidoreductase (NQO1) in Pancreatic Cancer. | 2017 Jul |
1 |
| 36 |
28694766 | Flavoenzyme-mediated reduction reactions and antitumor activity of nitrogen-containing tetracyclic ortho-quinone compounds and their nitrated derivatives. | 2017 |
1 |
| 37 |
28833669 | A Tumor-Specific Cascade Amplification Drug Release Nanoparticle for Overcoming Multidrug Resistance in Cancers. | 2017 Oct |
2 |
| 38 |
29153688 | Genetic association of the NQO1 rs1800566 (609C>T) variant with risk of preeclampsia in the Chinese Han population. | 2017 Oct |
1 |
| 39 |
26553038 | Depleting Tumor-NQO1 Potentiates Anoikis and Inhibits Growth of NSCLC. | 2016 Jan |
5 |
| 40 |
26681508 | Naphtho[1',2':4,5]imidazo[1,2-a]pyridine-5,6-diones: Synthesis, enzymatic reduction and cytotoxic activity. | 2016 Jan 15 |
2 |
| 41 |
26870816 | Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production. | 2016 Jan |
1 |
| 42 |
26935540 | NQO1 Deficiency Leads Enhanced Autophagy in Cisplatin-Induced Acute Kidney Injury Through the AMPK/TSC2/mTOR Signaling Pathway. | 2016 May 20 |
1 |
| 43 |
27539524 | [PM2.5 induces oxidative damage and affects nuclear factor-erythroid 2 related factor 2 pathway in human umbilical vein endothelial cells]. | 2016 Aug 6 |
1 |
| 44 |
27542238 | A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1. | 2016 Sep 27 |
1 |
| 45 |
25590809 | NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone. | 2015 Jan 15 |
5 |
| 46 |
25870517 | Expanding antitumor therapeutic windows by targeting cancer-specific nicotinamide adenine dinucleotide phosphate-biogenesis pathways. | 2015 |
2 |
| 47 |
26096359 | Synthesis and Intracellular Redox Cycling of Natural Quinones and Their Analogues and Identification of Indoleamine-2,3-dioxygenase (IDO) as Potential Target for Anticancer Activity. | 2015 Jul 20 |
2 |
| 48 |
26120483 | Computational Optimization of Bioanalytical Parameters for the Evaluation of the Toxicity of the Phytomarker 1,4 Napthoquinone and its Metabolite 1,2,4-trihydroxynapththalene. | 2015 Jun |
1 |
| 49 |
26295053 | Association of Environmental Arsenic Exposure, Genetic Polymorphisms of Susceptible Genes, and Skin Cancers in Taiwan. | 2015 |
1 |
| 50 |
24361488 | Nrf2/ARE pathway activation, HO-1 and NQO1 induction by polychlorinated biphenyl quinone is associated with reactive oxygen species and PI3K/AKT signaling. | 2014 Feb 25 |
1 |