Protein Name Rac family small GTPase 1
Organism Mus musculus
Gene ID 19353
Gene Symbol

Rac1

UniProt P63001 (RAC1_MOUSE), Q3TLP8 (Q3TLP8_MOUSE), K7Q7T7 (K7Q7T7_MOUSE)
Relationships Total Number of functionally related compound(s) : 323
Total Number of Articles : 525
Description

Rac family small GTPase 1

Gene Summary

Enables GTP binding activity; GTP-dependent protein binding activity; and GTPase activity. Involved in several processes, including engulfment of apoptotic cell; nervous system development; and regulation of cell migration. Acts upstream of or within several processes, including cell morphogenesis involved in differentiation; cochlea morphogenesis; and neuron differentiation. Located in several cellular components, including kinocilium; pericentriolar material; and ruffle membrane. Is extrinsic component of plasma membrane. Is expressed in several structures, including central nervous system; early conceptus; embryo mesoderm; eye; and genitourinary system. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 48; colon adenocarcinoma; and pancreatic adenocarcinoma. Orthologous to human RAC1 (Rac family small GTPase 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • ras-related C3 botulinum toxin substrate 1
  • RAS-related C3 botulinum substrate 1
  • p21-Rac1
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Properties