| Protein Name | Rac family small GTPase 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 19353 |
| Gene Symbol | Rac1 |
| UniProt | P63001 (RAC1_MOUSE), Q3TLP8 (Q3TLP8_MOUSE), K7Q7T7 (K7Q7T7_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
323
Total Number of Articles : 525 |
Description |
Rac family small GTPase 1 |
| Gene Summary |
Enables G protein activity; GTP binding activity; and GTP-dependent protein binding activity. Involved in several processes, including nervous system development; positive regulation of protein localization; and regulation of cell migration. Acts upstream of or within several processes, including actin filament polymerization; generation of neurons; and regulation of intracellular signal transduction. Located in several cellular components, including kinocilium; pericentriolar material; and ruffle membrane. Is active in glutamatergic synapse; synaptic membrane; and synaptic vesicle membrane. Is expressed in several structures, including early conceptus; eye; genitourinary system; nervous system; and organ of Corti. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 48; colorectal cancer (multiple); lung cancer; and pancreatic adenocarcinoma. Orthologous to human RAC1 (Rac family small GTPase 1). [provided by Alliance of Genome Resources, Jun 2025] |
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