Protein Name superoxide dismutase 1, soluble
Organism Mus musculus
Gene ID 20655
Gene Symbol

Sod1

UniProt P08228 (SODC_MOUSE)
Relationships Total Number of functionally related compound(s) : 689
Total Number of Articles : 1147
Description

superoxide dismutase 1, soluble

Gene Summary

Enables superoxide dismutase activity. Involved in axonal transport; negative regulation of inflammatory response; and positive regulation of phagocytosis. Acts upstream of or within several processes, including hydrogen peroxide biosynthetic process; muscle cell cellular homeostasis; and neurogenesis. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study amyotrophic lateral sclerosis type 1; dry eye syndrome; and low tension glaucoma. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; artery disease (multiple); eye disease (multiple); glucose metabolism disease (multiple); and neurodegenerative disease (multiple). Orthologous to human SOD1 (superoxide dismutase 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • superoxide dismutase [Cu-Zn]
  • Cu(2+)-Zn2+ superoxide dismutase
  • B430204E11Rik
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Properties