| Protein Name | interleukin 1 alpha |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3552 |
| Gene Symbol | IL1A |
| UniProt | P01583 (IL1A_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
2741
Total Number of Articles : 5067 |
Description |
interleukin 1 alpha |
| Gene Summary |
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008] |
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