Protein Name interleukin 1 alpha
Organism Homo sapiens
Gene ID 3552
Gene Symbol


UniProt P01583 (IL1A_HUMAN)
Relationships Total Number of functionally related compound(s) : 2741
Total Number of Articles : 5067

interleukin 1 alpha

Gene Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]

  • interleukin-1 alpha
  • hematopoietin-1
  • preinterleukin 1 alpha
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