Reactive Oxygen Species

mitogen-activated protein kinase 8 ; Rattus norvegicus







79 Article(s)
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1 34435888 Role of Nox4 in High Calcium-Induced Renal Oxidative Stress Damage and Crystal Deposition. 2022 Jan 2
2 35114838 BMSC-Derived ApoEVs Promote Craniofacial Bone Repair via ROS/JNK Signaling. 2022 Jun 1
3 35270009 Methylmercury Induces Mitochondria- and Endoplasmic Reticulum Stress-Dependent Pancreatic β-Cell Apoptosis via an Oxidative Stress-Mediated JNK Signaling Pathway. 2022 Mar 5 1
4 35527005 Dexmedetomidine attenuates acute stress-induced liver injury in rats by regulating the miR-34a-5p/ROS/JNK/p38 signaling pathway. 2022 1
5 32180463 Compression stress induces nucleus pulposus cell autophagy by inhibition of the PI3K/AKT/mTOR pathway and activation of the JNK pathway. 2021 May 2
6 33603672 Glycyrrhetinic Acid Protects Renal Tubular Cells against Oxidative Injury via Reciprocal Regulation of JNK-Connexin 43-Thioredoxin 1 Signaling. 2021 1
7 34109428 DHA ameliorates MeHg‑induced PC12 cell apoptosis by inhibiting the ROS/JNK signaling pathway. 2021 Aug 3
8 34367464 Advanced Oxidation Protein Products Induce G1/G0-Phase Arrest in Ovarian Granulosa Cells via the ROS-JNK/p38 MAPK-p21 Pathway in Premature Ovarian Insufficiency. 2021 1
9 31862514 Automobile exhaust-derived PM2.5 induces blood-testis barrier damage through ROS-MAPK-Nrf2 pathway in sertoli cells of rats. 2020 Feb 1
10 32428522 Activation of NADPH/ROS pathway contributes to angiogenesis through JNK signaling in brain endothelial cells. 2020 Sep 2
11 32498294 Urban Particulate Matter Enhances ROS/IL-6/COX-II Production by Inhibiting MicroRNA-137 in Synovial Fibroblast of Rheumatoid Arthritis. 2020 Jun 2 1
12 32810585 Lycopene ameliorates chronic stress-induced hippocampal injury and subsequent learning and memory dysfunction through inhibiting ROS/JNK signaling pathway in rats. 2020 Nov 2
13 32856499 Cadmium Chloride Induces Memory Deficits and Hippocampal Damage by Activating the JNK/p66Shc/NADPH Oxidase Axis. 2020 Sep/Oct 1
14 32948194 Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation. 2020 Sep 18 1
15 30617363 Lanthanum chloride induces autophagy in rat hippocampus through ROS-mediated JNK and AKT/mTOR signaling pathways. 2019 Feb 20 1
16 30991755 Green Tea Seed Oil Suppressed Aβ1⁻42-Induced Behavioral and Cognitive Deficit via the Aβ-Related Akt Pathway. 2019 Apr 15 1
17 31205589 N-n-Butyl Haloperidol Iodide Ameliorates Oxidative Stress in Mitochondria Induced by Hypoxia/Reoxygenation through the Mitochondrial c-Jun N-Terminal Kinase/Sab/Src/Reactive Oxygen Species Pathway in H9c2 Cells. 2019 1
18 31358627 Aging of spermatogonial stem cells by Jnk-mediated glycolysis activation. 2019 Aug 13 2
19 31519469 Double immunofluorescent evidence that oxidative stress-associated activation of JNK/AP-1 signaling participates in neuropeptide-mediated appetite control. 2019 Nov 2
20 29315209 The Bioactive Extract of Pinnigorgia sp. Induces Apoptosis of Hepatic Stellate Cells via ROS-ERK/JNK-Caspase-3 Signaling. 2018 Jan 9 1
21 29467841 Hepatoprotective effect of methyl ferulic acid against carbon tetrachloride-induced acute liver injury in rats. 2018 Mar 1
22 30250633 Dexmedetomidine Ameliorates Acute Stress-Induced Kidney Injury by Attenuating Oxidative Stress and Apoptosis through Inhibition of the ROS/JNK Signaling Pathway. 2018 2
23 27859591 Nrf2 Activation as a Protective Feedback to Limit Cell Death in High Glucose-Exposed Cardiomyocytes. 2017 Jul 2
24 28129433 Celastrol ameliorates Cd-induced neuronal apoptosis by targeting NOX2-derived ROS-dependent PP5-JNK signaling pathway. 2017 Apr 6
25 28590722 Injectable Fullerenol/Alginate Hydrogel for Suppression of Oxidative Stress Damage in Brown Adipose-Derived Stem Cells and Cardiac Repair. 2017 Jun 27 1
26 28656249 Oxidative stress regulates mitogen‑activated protein kinases and c‑Jun activation involved in heat stress and lipopolysaccharide‑induced intestinal epithelial cell apoptosis. 2017 Sep 1
27 28674486 Advanced Oxidative Protein Products Cause Pain Hypersensitivity in Rats by Inducing Dorsal Root Ganglion Neurons Apoptosis via NADPH Oxidase 4/c-Jun N-terminal Kinase Pathways. 2017 1
28 28678856 Time course of changes in oxidative stress and stress-induced proteins in cardiomyocytes exposed to doxorubicin and prevention by vitamin C. 2017 1
29 28822073 Isorhynchophylline Attenuates MPP+-Induced Apoptosis Through Endoplasmic Reticulum Stress- and Mitochondria-Dependent Pathways in PC12 Cells: Involvement of Antioxidant Activity. 2017 Dec 1
30 27989749 ROS-JNK1/2-dependent activation of autophagy is required for the induction of anti-inflammatory effect of dihydroartemisinin in liver fibrosis. 2016 Dec 1
31 25647547 Icariin protects H9c2 cardiomyocytes from lipopolysaccharide‑induced injury via inhibition of the reactive oxygen species‑dependent c‑Jun N‑terminal kinases/nuclear factor-κB pathway. 2015 Jun 2
32 25681429 Involvement of P2Y12 receptor in vascular smooth muscle inflammatory changes via MCP-1 upregulation and monocyte adhesion. 2015 Apr 15 2
33 25769956 Zerumbone protects INS-1 rat pancreatic beta cells from high glucose-induced apoptosis through generation of reactive oxygen species. 2015 May 1 1
34 25915446 Mechanism of rhein-induced apoptosis in rat primary hepatocytes: beneficial effect of cyclosporine A. 2015 Jun 15 1
35 26021285 EGb761 Ameliorates Neuropathic Pain by Scavenging Reactive Oxygen Species. 2015 1
36 26134032 Effect of N-n-butyl haloperidol iodide on ROS/JNK/Egr-1 signaling in H9c2 cells after hypoxia/reoxygenation. 2015 Jul 2 1
37 26195352 Hyperosmotic stress activates the expression of members of the miR-15/107 family and induces downregulation of anti-apoptotic genes in rat liver. 2015 Jul 21 2
38 26491537 Allopurinol Protects against Ischemia/Reperfusion-Induced Injury in Rat Urinary Bladders. 2015 1
39 24289330 FoxO3a modulation and promotion of apoptosis by interferon-α2b in rat preneoplastic liver. 2014 Nov 1
40 24294888 Valproic acid protects motor neuron death by inhibiting oxidative stress and endoplasmic reticulum stress-mediated cytochrome C release after spinal cord injury. 2014 Mar 15 6
41 24940396 Icariin attenuates angiotensin II-induced hypertrophy and apoptosis in H9c2 cardiomyocytes by inhibiting reactive oxygen species-dependent JNK and p38 pathways. 2014 May 2
42 24960051 Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson's disease. 2014 2
43 23158927 Diallyl trisufide (DATS) suppresses high glucose-induced cardiomyocyte apoptosis by inhibiting JNK/NFκB signaling via attenuating ROS generation. 2013 Sep 20 1
44 23258542 Inhibition of JNK mitochondrial localization and signaling is protective against ischemia/reperfusion injury in rats. 2013 Feb 8 4
45 23611574 Effect of free radical scavenger on c-jun activation in rats with crush syndrome. 2013 Jul 4
46 23969109 Heme oxygenase-1 induction by the ROS-JNK pathway plays a role in aluminum-induced anemia. 2013 Nov 10
47 21604272 NADPH oxidase-derived superoxide anion-induced apoptosis is mediated via the JNK-dependent activation of NF-κB in cardiomyocytes exposed to high glucose. 2012 Apr 1
48 22245600 High glucose induces renal mesangial cell proliferation and fibronectin expression through JNK/NF-κB/NADPH oxidase/ROS pathway, which is inhibited by resveratrol. 2012 Apr 3
49 22362362 ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes. 2012 May 2
50 23271287 Mechanisms of MPP⁺-induced PC12 cell apoptosis via reactive oxygen species. 2012 Dec 3