celastrol


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743 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 heat shock protein 90 alpha family class A member 1 HS90A_HUMAN HSP90AA1 Homo sapiens 3320 1552 39
2 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 35
3 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 30
4 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 28
5 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 24
6 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 22
7 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 21
8 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 19
9 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 19
10 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 17
11 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 17
12 cell division cycle 37, HSP90 cochaperone CDC37_HUMAN CDC37 Homo sapiens 11140 80 16
13 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 15
14 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 15
15 RELA proto-oncogene, NF-kB subunit TF65_HUMAN RELA Homo sapiens 5970 1514 14
16 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 13
17 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 13
18 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 12
19 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 11
20 heat shock protein family A (Hsp70) member 4 HSP74_HUMAN HSPA4 Homo sapiens 3308 1053 11
21 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 11
22 collagen type XI alpha 2 chain COBA2_HUMAN COL11A2 Homo sapiens 1302 794 11
23 NFKB inhibitor alpha IKBA_HUMAN NFKBIA Homo sapiens 4792 1043 11
24 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 11
25 heat shock transcription factor 1 HSF1_HUMAN HSF1 Homo sapiens 3297 337 10
26 NLR family, pyrin domain containing 3 NLRP3_MOUSE Nlrp3 Mus musculus 216799 1325 10
27 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 9
28 interleukin 1 beta IL1B_MOUSE Il1b Mus musculus 16176 2626 9
29 insulin INS_HUMAN INS Homo sapiens 3630 7950 8
30 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 8
31 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 8
32 toll like receptor 4 TLR4_HUMAN TLR4 Homo sapiens 7099 1426 8
33 interleukin 1 beta Q5BKB0_RAT Il1b Rattus norvegicus 24494 2252 8
34 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 8
35 intercellular adhesion molecule 1 ICAM1_HUMAN ICAM1 Homo sapiens 3383 1840 8
36 heme oxygenase 1 HMOX1_HUMAN HMOX1 Homo sapiens 3162 1764 8
37 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 7
38 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 7
39 heme oxygenase 1 HMOX1_RAT Hmox1 Rattus norvegicus 24451 1212 7
40 transforming growth factor, beta 1 TGFB1_MOUSE Tgfb1 Mus musculus 21803 1658 7
41 interleukin 6 IL6_RAT Il6 Rattus norvegicus 24498 2269 7
42 mechanistic target of rapamycin kinase MTOR_MOUSE Mtor Mus musculus 56717 1120 7
43 nitric oxide synthase 2, inducible NOS2_MOUSE Nos2 Mus musculus 18126 2585 7
44 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 7
45 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 6
46 synaptotagmin 1 SYT1_RAT Syt1 Rattus norvegicus 25716 704 6
47 leptin LEP_MOUSE Lep Mus musculus 16846 647 6
48 high mobility group box 1 HMGB1_RAT Hmgb1 Rattus norvegicus 25459 478 6
49 matrix metallopeptidase 2 MMP2_HUMAN MMP2 Homo sapiens 4313 2342 6
50 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 6