celastrol

BCL2 apoptosis regulator ; Homo sapiens







24 Article(s)
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1 34000513 Tripterine and miR-184 show synergy to suppress breast cancer progression. 2021 Jul 5 1
2 30389635 Celastrol strongly inhibits proliferation, migration and cancer stem cell properties through suppression of Pin1 in ovarian cancer cells. 2019 Jan 5 1
3 30668359 Celastrol induces vincristine multidrug resistance oral cancer cell apoptosis by targeting JNK1/2 signaling pathway. 2019 Feb 15 1
4 30867764 Efficacy of celastrol combined with cisplatin in enhancing the apoptosis of U-2OS osteosarcoma cells via the mitochondrial and endoplasmic reticulum pathways of apoptosis. 2019 Mar 1
5 29434967 Celastrol suppresses the proliferation of lung adenocarcinoma cells by regulating microRNA-24 and microRNA-181b. 2018 Feb 3
6 30255683 [Inhibition of proliferation of adult T-cell leukemia cells by celastrol]. 2018 Sep 25 2
7 30626478 [Celastrol inhibits growth and increases apoptosis of human lung cancer A549 cells]. 2018 Dec 4
8 28459364 Cytotoxic effect of celastrol alone or in combination with paclitaxel on anaplastic thyroid carcinoma cells. 2017 May 1
9 28522217 Celastrol inhibits chondrosarcoma proliferation, migration and invasion through suppression CIP2A/c-MYC signaling pathway. 2017 May 1
10 25818165 Anticancer effect of celastrol on human triple negative breast cancer: possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt pathways. 2015 Jun 1
11 26165547 Celastrol induces apoptosis of human osteosarcoma cells via the mitochondrial apoptotic pathway. 2015 Sep 1
12 24214023 Celastrol from 'Thunder God Vine' protects SH-SY5Y cells through the preservation of mitochondrial function and inhibition of p38 MAPK in a rotenone model of Parkinson's disease. 2014 Jan 1
13 24685625 Celastrol enhances cell viability and inhibits amyloid-β production induced by lipopolysaccharide in vitro. 2014 2
14 24755677 NF-kappa B modulation is involved in celastrol induced human multiple myeloma cell apoptosis. 2014 1
15 25310109 Celastrol induces the apoptosis of breast cancer cells and inhibits their invasion via downregulation of MMP-9. 2014 Dec 2
16 23711145 Celastrol induced DNA damage, cell cycle arrest, and apoptosis in human rheumatoid fibroblast-like synovial cells. 2013 1
17 22877649 Beta-catenin mediates the apoptosis induction effect of celastrol in HT29 cells. 2012 Sep 17 1
18 21134410 Celastrol isolated from Tripterygium regelii induces apoptosis through both caspase-dependent and -independent pathways in human breast cancer cells. 2011 Feb 1
19 21425580 [Effect of celastrol on Akt signaling pathway and apoptosis of leukemic K562 cell line]. 2011 Feb 1
20 21466843 Celastrol induces apoptosis in non-small-cell lung cancer A549 cells through activation of mitochondria- and Fas/FasL-mediated pathways. 2011 Aug 1
21 21951963 Celastrol-induced apoptosis in human HaCaT keratinocytes involves the inhibition of NF-κB activity. 2011 Nov 30 1
22 16984800 Inhibition of NF-kappa B activation through targeting I kappa B kinase by celastrol, a quinone methide triterpenoid. 2006 Nov 15 1
23 12508653 [Several monomes from Tripterygium wilfordii inhibit proliferation of glioma cells in vitro]. 2002 Oct 2
24 11601243 [In vitro study on cellular and molecular mechanism of tripterine treating leukemic mast cells]. 1999 Mar 2