celastrol

caspase 3 ; Homo sapiens







30 Article(s)
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1 35123623 [Effect of Celastrol Based on IRAK4/ERK/p38 Signaling Pathway on Proliferation and Apoptosis of Multiple Myeloma Cells]. 2022 Feb 1
2 33945201 Celastrol inhibit the proliferation, invasion and migration of human cervical HeLa cancer cells through down-regulation of MMP-2 and MMP-9. 2021 Jun 2
3 34560609 Targeted inhibition of TAK1 abrogates TGFβ1 non-canonical signaling axis, NFκB/Smad7 inhibiting human endometriotic cells proliferation and inducing cell death involving autophagy. 2021 Dec 1
4 31949255 Metabolomics Reveals that Cysteine Metabolism Plays a Role in Celastrol-Induced Mitochondrial Apoptosis in HL-60 and NB-4 Cells. 2020 Jan 16 1
5 30389635 Celastrol strongly inhibits proliferation, migration and cancer stem cell properties through suppression of Pin1 in ovarian cancer cells. 2019 Jan 5 1
6 30569150 Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species. 2019 Feb 1
7 30668359 Celastrol induces vincristine multidrug resistance oral cancer cell apoptosis by targeting JNK1/2 signaling pathway. 2019 Feb 15 1
8 30867764 Efficacy of celastrol combined with cisplatin in enhancing the apoptosis of U-2OS osteosarcoma cells via the mitochondrial and endoplasmic reticulum pathways of apoptosis. 2019 Mar 1
9 31281953 Celastrol enhances TRAIL-induced apoptosis in human glioblastoma via the death receptor pathway. 2019 Oct 1
10 29534015 Targeting Hodgkin and Reed-Sternberg Cells with an Inhibitor of Heat-Shock Protein 90: Molecular Pathways of Response and Potential Mechanisms of Resistance. 2018 Mar 13 1
11 29928421 The coordinated effects of Apatinib and Tripterine on the proliferation, invasiveness and apoptosis of human hepatoma Hep3B cells. 2018 Jul 2
12 30255683 [Inhibition of proliferation of adult T-cell leukemia cells by celastrol]. 2018 Sep 25 1
13 30626478 [Celastrol inhibits growth and increases apoptosis of human lung cancer A549 cells]. 2018 Dec 2
14 25611379 Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells: an in vitro and in vivo study. 2015 Jan 22 2
15 25657108 Celastrol induces mitochondria-mediated apoptosis in hepatocellular carcinoma Bel-7402 cells. 2015 2
16 25818165 Anticancer effect of celastrol on human triple negative breast cancer: possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt pathways. 2015 Jun 1
17 26165547 Celastrol induces apoptosis of human osteosarcoma cells via the mitochondrial apoptotic pathway. 2015 Sep 1
18 24111524 Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network. 2014 Jan 1
19 24755677 NF-kappa B modulation is involved in celastrol induced human multiple myeloma cell apoptosis. 2014 1
20 25310109 Celastrol induces the apoptosis of breast cancer cells and inhibits their invasion via downregulation of MMP-9. 2014 Dec 1
21 23142250 Effects of celastrol on human cervical cancer cells as revealed by ion-trap gas chromatography-mass spectrometry based metabolic profiling. 2013 Mar 1
22 23649759 Celastrol exerts synergistic effects with PHA-665752 and inhibits tumor growth of c-Met-deficient hepatocellular carcinoma in vivo. 2013 Jul 1
23 23711145 Celastrol induced DNA damage, cell cycle arrest, and apoptosis in human rheumatoid fibroblast-like synovial cells. 2013 1
24 21466843 Celastrol induces apoptosis in non-small-cell lung cancer A549 cells through activation of mitochondria- and Fas/FasL-mediated pathways. 2011 Aug 1
25 21506956 Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells. 2011 Nov 1
26 21569548 Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells. 2011 May 14 1
27 21786165 Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways. 2011 Oct 1
28 21850367 Quinone methide tripterine, celastrol, induces apoptosis in human myeloma cells via NF-κB pathway. 2011 Nov 1
29 21951963 Celastrol-induced apoptosis in human HaCaT keratinocytes involves the inhibition of NF-κB activity. 2011 Nov 30 1
30 20154087 Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors. 2010 Apr 9 1