Protein Name synaptotagmin 1
Organism Rattus norvegicus
Gene ID 25716
Gene Symbol

Syt1

UniProt P21707 (SYT1_RAT), Q707P0 (Q707P0_RAT)
Relationships Total Number of functionally related compound(s) : 704
Total Number of Articles : 965
Description

synaptotagmin 1

Gene Summary

Enables several functions, including calmodulin binding activity; phospholipid binding activity; and syntaxin binding activity. Involved in several processes, including positive regulation of dopamine secretion; regulation of vesicle-mediated transport; and response to calcium ion. Located in several cellular components, including excitatory synapse; neuron projection terminus; and secretory vesicle. Is active in hippocampal mossy fiber to CA3 synapse. Is integral component of synaptic vesicle membrane. Biomarker of visual epilepsy. Orthologous to human SYT1 (synaptotagmin 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • synaptotagmin-1
  • synaptotagmin I
  • sytI
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Properties