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35107368 | p17-Modulated Hsp90/Cdc37 Complex Governs Oncolytic Avian Reovirus Replication by Chaperoning p17, Which Promotes Viral Protein Synthesis and Accumulation of Viral Proteins σC and σA in Viral Factories. | 2022 Mar 23 |
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35238566 | Discovery of Novel Celastrol-Imidazole Derivatives with Anticancer Activity In Vitro and In Vivo. | 2022 Mar 24 |
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33845380 | Discovery of novel celastrol-triazole derivatives with Hsp90-Cdc37 disruption to induce tumor cell apoptosis. | 2021 Jun |
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34170694 | Synthesis and Biological Evaluation of Celastrol Derivatives with Improved Cytotoxic Selectivity and Antitumor Activities. | 2021 Jul 23 |
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31051401 | Design, synthesis and antitumor evaluation of novel celastrol derivatives. | 2019 Jul 15 |
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31725288 | Discovery of Novel Celastrol Derivatives as Hsp90-Cdc37 Interaction Disruptors with Antitumor Activity. | 2019 Dec 12 |
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30588010 | Celastrol induces ubiquitin-dependent degradation of mTOR in breast cancer cells. | 2018 |
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27398312 | Mutations Y493G and K546D in human HSP90 disrupt binding of celastrol and reduce interaction with Cdc37. | 2016 Jul |
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27647369 | Optimization and biological evaluation of celastrol derivatives as Hsp90-Cdc37 interaction disruptors with improved druglike properties. | 2016 Nov 1 |
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25989799 | Withaferin A Regulates LRRK2 Levels by Interfering with the Hsp90- Cdc37 Chaperone Complex. | 2015 |
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24351928 | Celastrol increases glucocerebrosidase activity in Gaucher disease by modulating molecular chaperones. | 2014 Jan 7 |
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24056254 | Expression and purification of recombinant NRL-Hsp90α and Cdc37-CRL proteins for in vitro Hsp90/Cdc37 inhibitors screening. | 2013 Nov |
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20226165 | Celastrol: Molecular targets of Thunder God Vine. | 2010 Apr 9 |
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20480272 | Celastrol regulates multiple nuclear transcription factors belonging to HSP90's clients in a dose- and cell type-dependent way. | 2010 Nov |
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19585625 | Molecular mechanism of inhibition of the human protein complex Hsp90-Cdc37, a kinome chaperone-cochaperone, by triterpene celastrol. | 2009 |
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19858214 | Characterization of celastrol to inhibit hsp90 and cdc37 interaction. | 2009 Dec 18 |
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