celastrol

mechanistic target of rapamycin kinase ; Homo sapiens







22 Article(s)
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1 34053427 Celastrol Inhibits the Proliferation and Decreases Drug Resistance of Cisplatin- Resistant Gastric Cancer SGC7901/DDP Cells. 2022 5
2 33870466 Comparative transcriptomics and network pharmacology analysis to identify the potential mechanism of celastrol against osteoarthritis. 2021 Oct 2
3 34114395 Celastrol induces caspase-dependent apoptosis of hepatocellular carcinoma cells by suppression of mammalian target of rapamycin. 2021 Jun 4
4 34326694 Celastrol ameliorates vascular neointimal hyperplasia through Wnt5a-involved autophagy. 2021 1
5 34982057 Celastrol promotes chondrocyte autophagy by regulating mTOR expression. 2021 Jun 15 1
6 32116702 Celastrol Suppresses Glioma Vasculogenic Mimicry Formation and Angiogenesis by Blocking the PI3K/Akt/mTOR Signaling Pathway. 2020 3
7 30709873 Correction: Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway. 2019 Feb 1 1
8 31053160 Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells. 2019 May 3 3
9 31266528 Correction to: Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells. 2019 Jul 2 1
10 29484434 miR-33a-5p enhances the sensitivity of lung adenocarcinoma cells to celastrol by regulating mTOR signaling. 2018 Apr 5
11 30588010 Celastrol induces ubiquitin-dependent degradation of mTOR in breast cancer cells. 2018 10
12 27764525 Celastrol prevents cadmium-induced neuronal cell death by blocking reactive oxygen species-mediated mammalian target of rapamycin pathway. 2017 Jan 6
13 27891586 Celastrol Attenuates Cadmium-Induced Neuronal Apoptosis via Inhibiting Ca2+ -CaMKII-Dependent Akt/mTOR Pathway. 2017 Aug 6
14 27671821 Celastrol and Its Role in Controlling Chronic Diseases. 2016 1
15 25818165 Anticancer effect of celastrol on human triple negative breast cancer: possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt pathways. 2015 Jun 3
16 26500453 Celastrol induces cell cycle arrest by MicroRNA-21-mTOR-mediated inhibition p27 protein degradation in gastric cancer. 2015 4
17 26552919 Inhibiting inducible miR-223 further reduces viable cells in human cancer cell lines MCF-7 and PC3 treated by celastrol. 2015 Nov 9 4
18 24111524 Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network. 2014 Jan 7
19 24667175 Celastrol inhibits gastric cancer growth by induction of apoptosis and autophagy. 2014 Dec 1
20 24859482 Celastrol inhibits the HIF-1α pathway by inhibition of mTOR/p70S6K/eIF4E and ERK1/2 phosphorylation in human hepatoma cells. 2014 Jul 3
21 21168266 Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer. 2011 Apr 1 1
22 20160026 Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway. 2010 Mar 1 5