celastrol

NLR family, pyrin domain containing 3 ; Mus musculus







10 Article(s)
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1 35605435 Phytosomal tripterine with selenium modification attenuates the cytotoxicity and restrains the inflammatory evolution via inhibiting NLRP3 inflammasome activation and pyroptosis. 2022 Jul 1
2 32176932 Enhanced Inflammatory Reaction and Thrombosis in High-Fat Diet-Fed ApoE-/- Mice are Attenuated by Celastrol. 2021 May 1
3 32776627 Celastrol alleviates metabolic disturbance in high-fat diet-induced obese mice through increasing energy expenditure by ameliorating metabolic inflammation. 2021 Jan 1
4 33130474 Celastrol ameliorates Propionibacterium acnes/LPS-induced liver damage and MSU-induced gouty arthritis via inhibiting K63 deubiquitination of NLRP3. 2021 Jan 1
5 33559709 Tripterine ameliorates monosodium urate crystal-induced gouty arthritis by altering macrophage polarization via the miR-449a/NLRP3 axis. 2021 Mar 1
6 34600334 The Nrf2-NLRP3-caspase-1 axis mediates the neuroprotective effects of Celastrol in Parkinson's disease. 2021 Nov 5
7 31989218 Novel complementary antitumour effects of celastrol and metformin by targeting IκBκB, apoptosis and NLRP3 inflammasome activation in diethylnitrosamine-induced murine hepatocarcinogenesis. 2020 Feb 2
8 32953791 Micheliolide alleviates ankylosing spondylitis (AS) by suppressing the activation of the NLRP3 inflammasome and maintaining the balance of Th1/Th2 via regulating the NF-κB signaling pathway. 2020 Aug 1
9 30472522 Celastrol inhibits microglial pyroptosis and attenuates inflammatory reaction in acute spinal cord injury rats. 2019 Jan 1
10 31439870 Inhibition of NLRP3 inflammasome in tumor microenvironment leads to suppression of metastatic potential of cancer cells. 2019 Aug 22 1