celastrol

nuclear factor kappa B subunit 1 ; Homo sapiens







35 Article(s)
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1 34732120 Celastrol Inhibits the Proliferation and Induces Apoptosis of Colorectal Cancer Cells via Downregulating NF-κB/COX-2 Signaling Pathways. 2022 2
2 35282664 Celastrol attenuates the remodeling of pulmonary vascular and right ventricular in monocrotaline-induced pulmonary arterial hypertension in rats. 2022 Feb 1
3 35530963 Regulating mitochondrial homeostasis and inhibiting inflammatory responses through Celastrol. 2022 Apr 1
4 34072312 Multiple Myeloma Inhibitory Activity of Plant Natural Products. 2021 May 29 1
5 34147915 Celastrol inhibits rheumatoid arthritis through the ROS-NF-κB-NLRP3 inflammasome axis. 2021 Sep 1
6 34285658 Effect of Lipopolysaccharide and TNFα on Neuronal Ascorbic Acid Uptake. 2021 1
7 34702273 Celastrol-based nanomedicine promotes corneal allograft survival. 2021 Oct 26 1
8 32041250 Celastrol Alleviates Gamma Irradiation-Induced Damage by Modulating Diverse Inflammatory Mediators. 2020 Feb 6 1
9 32818610 Combination of magnetic targeting with synergistic inhibition of NF-κB and glutathione via micellar drug nanomedicine enhances its anti-tumor efficacy. 2020 Oct 1
10 32920591 Celastrol Inhibits Migration and Invasion of Triple-Negative Breast Cancer Cells by Suppressing Interleukin-6 via Downregulating Nuclear Factor-κB (NF-κB). 2020 Sep 13 6
11 32965124 Inflammation-Targeted Celastrol Nanodrug Attenuates Collagen-Induced Arthritis through NF-κB and Notch1 Pathways. 2020 Oct 14 1
12 29631379 Tumor necrosis factor alpha reduces intestinal vitamin C uptake: a role for NF-κB-mediated signaling. 2018 Aug 1 1
13 28027722 Celastrol suppresses expression of adhesion molecules and chemokines by inhibiting JNK-STAT1/NF-κB activation in poly(I:C)-stimulated astrocytes. 2017 Jan 3
14 27484716 Celastrol inhibits IL-1β-induced inflammation in orbital fibroblasts through the suppression of NF-κB activity. 2016 Sep 1
15 27900015 Celastrol negatively regulates cell invasion and migration ability of human osteosarcoma via downregulation of the PI3K/Akt/NF-κB signaling pathway in vitro. 2016 Nov 3
16 25941817 Celastrol inhibits inflammatory stimuli-induced neutrophil extracellular trap formation. 2015 1
17 24157922 Celastrol inhibits lipopolysaccharide-induced angiogenesis by suppressing TLR4-triggered nuclear factor-kappa B activation. 2014 4
18 24434352 Celastrol induces apoptosis of gastric cancer cells by miR-21 inhibiting PI3K/Akt-NF-κB signaling pathway. 2014 6
19 24465597 A new multicolor bioluminescence imaging platform to investigate NF-κB activity and apoptosis in human breast cancer cells. 2014 1
20 24664372 Celastrol blocks interleukin-6 gene expression via downregulation of NF-κB in prostate carcinoma cells. 2014 8
21 24685625 Celastrol enhances cell viability and inhibits amyloid-β production induced by lipopolysaccharide in vitro. 2014 2
22 24755677 NF-kappa B modulation is involved in celastrol induced human multiple myeloma cell apoptosis. 2014 3
23 25474091 Amelioration of mitochondrial dysfunction-induced insulin resistance in differentiated 3T3-L1 adipocytes via inhibition of NF-κB pathways. 2014 Dec 2 1
24 23396231 Celastrol, an inhibitor of heat shock protein 90β potently suppresses the expression of matrix metalloproteinases, inducible nitric oxide synthase and cyclooxygenase-2 in primary human osteoarthritic chondrocytes. 2013 May 15 2
25 23988648 miR-224 is critical for celastrol-induced inhibition of migration and invasion of hepatocellular carcinoma cells. 2013 5
26 22954486 Celastrol inhibits interleukin-17A-stimulated rheumatoid fibroblast-like synoviocyte migration and invasion through suppression of NF-κB-mediated matrix metalloproteinase-9 expression. 2012 Dec 5
27 21088503 Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers. 2011 Jan 15 1
28 21683142 Celastrol regulates innate immunity response via NF-κB and Hsp70 in human retinal pigment epithelial cells. 2011 Nov 6
29 21850367 Quinone methide tripterine, celastrol, induces apoptosis in human myeloma cells via NF-κB pathway. 2011 Nov 2
30 21865725 Celastrol inhibits breast cancer cell invasion via suppression of NF-ĸB-mediated matrix metalloproteinase-9 expression. 2011 3
31 20346213 Effects of Celastrol on growth inhibition of U937 leukemia cells through the regulation of the Notch1/NF-kappaB signaling pathway in vitro. 2010 Apr 1
32 21170316 Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB. 2010 Dec 10 5
33 19778460 The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma. 2009 Sep 25 3
34 19934274 Celastrol synergistically enhances temozolomide cytotoxicity in melanoma cells. 2009 Dec 3
35 16984800 Inhibition of NF-kappa B activation through targeting I kappa B kinase by celastrol, a quinone methide triterpenoid. 2006 Nov 15 7