Caffeine


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1702 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 cytochrome P450 family 1 subfamily A member 2 CP1A2_HUMAN CYP1A2 Homo sapiens 1544 1532 328
2 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 99
3 ryanodine receptor 1 RYR1_HUMAN RYR1 Homo sapiens 6261 451 78
4 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 73
5 ATR serine/threonine kinase ATR_HUMAN ATR Homo sapiens 545 866 70
6 adenosine A2a receptor AA2AR_HUMAN ADORA2A Homo sapiens 135 406 64
7 insulin INS_HUMAN INS Homo sapiens 3630 7950 54
8 N-acetyltransferase 2 ARY2_HUMAN NAT2 Homo sapiens 10 326 52
9 carbonic anhydrase 2 CAH2_RAT Car2 Rattus norvegicus 54231 879 50
10 ryanodine receptor 2 RYR2_HUMAN RYR2 Homo sapiens 6262 272 49
11 carbonic anhydrase 2 CAH2_HUMAN CA2 Homo sapiens 760 1845 39
12 adenosine A2a receptor AA2AR_MOUSE Adora2a Mus musculus 11540 275 38
13 ryanodine receptor 1, skeletal muscle RYR1_MOUSE Ryr1 Mus musculus 20190 163 38
14 ryanodine receptor 2 RYR2_RAT Ryr2 Rattus norvegicus 689560 235 34
15 cytochrome P450, family 1, subfamily a, polypeptide 2 CP1A2_RAT Cyp1a2 Rattus norvegicus 24297 673 32
16 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 29
17 cytochrome P450 family 4 subfamily F member 3 CP4F3_HUMAN CYP4F3 Homo sapiens 4051 2473 28
18 Fos proto-oncogene, AP-1 transcription factor subunit FOS_RAT Fos Rattus norvegicus 314322 1662 28
19 cyclin dependent kinase 1 CDK1_HUMAN CDK1 Homo sapiens 983 1023 26
20 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 26
21 carbonic anhydrase 1 CAH1_RAT Car1 Rattus norvegicus 310218 1725 20
22 caffeine susceptibility - Caf Mus musculus 104272 66 20
23 lysine acetyltransferase 2B KAT2B_HUMAN KAT2B Homo sapiens 8850 295 19
24 cytochrome P450 family 2 subfamily A member 6 CP2A6_HUMAN CYP2A6 Homo sapiens 1548 512 18
25 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 18
26 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 18
27 LOW QUALITY PROTEIN: carbonic anhydrase 2 - LOC100719293 Cavia porcellus 100719293 166 18
28 transformation related protein 53, pseudogene - Trp53-ps Mus musculus 22060 1552 18
29 brain-derived neurotrophic factor BDNF_RAT Bdnf Rattus norvegicus 24225 1357 17
30 checkpoint kinase 2 CHK2_HUMAN CHEK2 Homo sapiens 11200 417 17
31 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 17
32 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 16
33 adenosine A2a receptor AA2AR_RAT Adora2a Rattus norvegicus 25369 260 15
34 adenosine A1 receptor AA1R_MOUSE Adora1 Mus musculus 11539 190 14
35 ryanodine receptor 2, cardiac RYR2_MOUSE Ryr2 Mus musculus 20191 118 14
36 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 14
37 renin RENI_HUMAN REN Homo sapiens 5972 1345 14
38 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 13
39 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 13
40 CD59 molecule (CD59 blood group) CD59_HUMAN CD59 Homo sapiens 966 1815 13
41 angiotensinogen ANGT_RAT Agt Rattus norvegicus 24179 2598 12
42 immunoglobulin kappa variable 1-16 - IGKV1-16 Homo sapiens 28938 866 12
43 selenium binding protein 1 SBP1_HUMAN SELENBP1 Homo sapiens 8991 688 12
44 cyclin dependent kinase inhibitor 1A CDN1A_HUMAN CDKN1A Homo sapiens 1026 1631 12
45 ryanodine receptor 3 RYR3_HUMAN RYR3 Homo sapiens 6263 42 12
46 interleukin 10 IL10_HUMAN IL10 Homo sapiens 3586 2075 11
47 renin RENI_RAT Ren Rattus norvegicus 24715 940 11
48 cytochrome P450, family 1, subfamily a, polypeptide 2 CP1A2_MOUSE Cyp1a2 Mus musculus 13077 215 11
49 ataxia telangiectasia and Rad3 related E9QPK4_MOUSE Atr Mus musculus 245000 84 11
50 activation induced cytidine deaminase AICDA_HUMAN AICDA Homo sapiens 57379 912 11