| 1 |
34078115 | Impact of Interferons and Biological Drug Inhibitors of IL-2 and IL-6 on Small-Molecule Drug Metabolism Through the Cytochrome P450 System. | 2022 Feb |
2 |
| 2 |
34564706 | CYP1A2 polymorphisms modify the association of habitual coffee consumption with appetite, macronutrient intake, and body mass index: results from an observational cohort and a cross-over randomized study. | 2022 Jan |
2 |
| 3 |
34611052 | CYP1A2 Genotype Polymorphism Influences the Effect of Caffeine on Anaerobic Performance in Trained Males. | 2022 Jan 1 |
2 |
| 4 |
34697258 | Comment on "CYP1A2 Genotype Modifies the Effects of Caffeine Compared With Placebo on Muscle Strength in Competitive Male Athletes". | 2022 Jan 1 |
1 |
| 5 |
35139770 | Spectroscopic observations of β-eudesmol binding to human cytochrome P450 isoforms 3A4 and 1A2, but not to isoforms 2C9, 2C19, and 2D6. | 2022 Feb |
2 |
| 6 |
33137206 | CYP1A2 genotype and acute ergogenic effects of caffeine intake on exercise performance: a systematic review. | 2021 Apr |
3 |
| 7 |
33170731 | Caffeine, exercise physiology, and time-trial performance: no effect of ADORA2A or CYP1A2 genotypes. | 2021 Jun |
1 |
| 8 |
33336382 | Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2. | 2021 Jun |
1 |
| 9 |
33397254 | Metabolism and Mechanism of Human Cytochrome P450 Enzyme 1A2. | 2021 |
1 |
| 10 |
33403509 | Novel insights on caffeine supplementation, CYP1A2 genotype, physiological responses and exercise performance. | 2021 Mar |
4 |
| 11 |
33764424 | Association Between Maternal Caffeine Consumption and Metabolism and Neonatal Anthropometry: A Secondary Analysis of the NICHD Fetal Growth Studies-Singletons. | 2021 Mar 1 |
1 |
| 12 |
33849480 | Caffeine-clozapine interaction associated with severe toxicity and multiorgan system failure: a case report. | 2021 Apr 13 |
1 |
| 13 |
33951339 | A Phase 1 Open-Label, Fixed-Sequence Pharmacokinetic Drug Interaction Trial to Investigate the Effect of Cannabidiol on the CYP1A2 Probe Caffeine in Healthy Subjects. | 2021 Nov |
1 |
| 14 |
34041763 | Simultaneous quantitation of serum caffeine and its metabolites by ultra-high-performance liquid chromatography-tandem mass spectrometry for CYP1A2 activity prediction in premature infants. | 2021 Sep |
5 |
| 15 |
34053199 | Data-driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment. | 2021 Jul |
1 |
| 16 |
34284351 | CYP1A2 Genotype Modifies the Effects of Caffeine Compared With Placebo on Muscle Strength in Competitive Male Athletes. | 2021 Sep 1 |
2 |
| 17 |
34352333 | OpenCYP: An open source database exploring human variability in activities and frequencies of polymophisms for major cytochrome P-450 isoforms across world populations. | 2021 Oct 10 |
1 |
| 18 |
34364467 | The determination of the Paraxanthine/Caffeine ratio as a metabolic biomarker for CYP1A2 activity in various human matrices by UHPLC-ESIMS/MS. | 2021 Nov 1 |
1 |
| 19 |
34391463 | Association between hypertension and coffee drinking based on CYP1A2 rs762551 single nucleotide polymorphism in Taiwanese. | 2021 Aug 14 |
2 |
| 20 |
34527815 | Time effect of rutaecarpine on caffeine pharmacokinetics in rats. | 2021 Dec |
1 |
| 21 |
34529114 | Caffeine, genetic variation and anaerobic performance in male athletes: a randomized controlled trial. | 2021 Dec |
1 |
| 22 |
34602096 | Pharmacokinetics of caffeine self-administered in overdose in a Japanese patient admitted to hospital. | 2021 Oct 4 |
1 |
| 23 |
35280254 | Pharmacokinetics of Caffeine: A Systematic Analysis of Reported Data for Application in Metabolic Phenotyping and Liver Function Testing. | 2021 |
2 |
| 24 |
31608602 | Cytochrome P450 1A2 activity and incidence of thyroid disease and cancer after chronic or acute exposure to dioxins. | 2020 Mar |
2 |
| 25 |
31610604 | [Caffeine, the most frequently consumed psychostimulant: a narrative review article]. | 2020 May |
1 |
| 26 |
31658882 | Impact of peripheral mutations on the access channels of human cytochrome P450 1A2. | 2020 Oct |
1 |
| 27 |
31744669 | Validation of a sensitive UHPLC-MS/MS method for cytochrome P450 probe substrates caffeine, tolbutamide, dextromethorphan, and alprazolam in human serum reveals drug contamination of serum used for research. | 2020 Feb 5 |
1 |
| 28 |
32050158 | An improved cytochrome P450 phenotyping cocktail with a simplified and highly sensitive UHPLC-MS/MS assay in human plasma. | 2020 Mar 1 |
1 |
| 29 |
32071850 | Is there a sex difference in adult salivary clearance of caffeine (1,3,7-trimethylpurine-2,6-dione)? | 2020 Apr-Jun |
1 |
| 30 |
32295624 | CYP1A2 genotype and acute effects of caffeine on resistance exercise, jumping, and sprinting performance. | 2020 Apr 15 |
1 |
| 31 |
32356023 | The effect of caffeine on cognitive performance is influenced by CYP1A2 but not ADORA2A genotype, yet neither genotype affects exercise performance in healthy adults. | 2020 Jul |
3 |
| 32 |
32424513 | CYP1A2 rs762551 and ADORA2A rs5760423 Polymorphisms in Patients with Blepharospasm. | 2020 Sep |
1 |
| 33 |
32538495 | Caffeine improves various aspects of athletic performance in adolescents independent of their 163 C > A CYP1A2 genotypes. | 2020 Oct |
2 |
| 34 |
32569126 | Effect of Caffeine on Endurance Performance in Athletes May Depend on HTR2A and CYP1A2 Genotypes. | 2020 Jun 17 |
3 |
| 35 |
32823594 | Effects of CYP1A2 and ADORA2A Genotypes on the Ergogenic Response to Caffeine in Professional Handball Players. | 2020 Aug 13 |
5 |
| 36 |
32941854 | Asenapine and iloperidone decrease the expression of major cytochrome P450 enzymes CYP1A2 and CYP3A4 in human hepatocytes. A significance for drug-drug interactions during combined therapy. | 2020 Nov 1 |
1 |
| 37 |
33302490 | A Physiologically-Based Pharmacokinetic (PBPK) Model Network for the Prediction of CYP1A2 and CYP2C19 Drug-Drug-Gene Interactions with Fluvoxamine, Omeprazole, S-mephenytoin, Moclobemide, Tizanidine, Mexiletine, Ethinylestradiol, and Caffeine. | 2020 Dec 8 |
1 |
| 38 |
33374269 | Simultaneous Quantification of Antioxidants Paraxanthine and Caffeine in Human Saliva by Electrochemical Sensing for CYP1A2 Phenotyping. | 2020 Dec 24 |
2 |
| 39 |
29532291 | The effect of CYP1A2 genotype on the ergogenic properties of caffeine during resistance exercise: a randomized, double-blind, placebo-controlled, crossover study. | 2019 Feb |
3 |
| 40 |
30387917 | Effects of Common CYP1A2 Genotypes and Other Key Factors on Intraindividual Variation in the Caffeine Metabolic Ratio: An Exploratory Analysis. | 2019 Jan |
2 |
| 41 |
30689395 | Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Caffeine Disposition in Pregnancy. | 2019 Mar 4 |
2 |
| 42 |
30762305 | Physiologically-Based Pharmacokinetic Models for CYP1A2 Drug-Drug Interaction Prediction: A Modeling Network of Fluvoxamine, Theophylline, Caffeine, Rifampicin, and Midazolam. | 2019 May |
1 |
| 43 |
30773300 | Influence of genetic polymorphisms and habitual caffeine intake on the changes in blood pressure, pulse rate, and calculation speed after caffeine intake: A prospective, double blind, randomized trial in healthy volunteers. | 2019 Mar |
1 |
| 44 |
30838377 | Long-term coffee consumption, caffeine metabolism genetics, and risk of cardiovascular disease: a prospective analysis of up to 347,077 individuals and 8368 cases. | 2019 Mar 1 |
2 |
| 45 |
31132250 | Binding Modes and Metabolism of Caffeine. | 2019 Jul 15 |
1 |
| 46 |
31164617 | Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy. | 2019 May 13 |
1 |
| 47 |
31324842 | Genetic Polymorphisms in ADORA2A and CYP1A2 Influence Caffeine's Effect on Postprandial Glycaemia. | 2019 Jul 19 |
3 |
| 48 |
31339646 | CYP2B6 Genotype-Dependent Inhibition of CYP1A2 and Induction of CYP2A6 by the Antiretroviral Drug Efavirenz in Healthy Volunteers. | 2019 Nov |
1 |
| 49 |
31519293 | Caffeine/Angelica dahurica and caffeine/Salvia miltiorrhiza metabolic inhibition in humans: In vitro and in vivo studies. | 2019 Oct |
1 |
| 50 |
28853006 | Are the Current Guidelines on Caffeine Use in Sport Optimal for Everyone? Inter-individual Variation in Caffeine Ergogenicity, and a Move Towards Personalised Sports Nutrition. | 2018 Jan |
1 |