| 1 |
33101488 | Small molecule 2,3-DCPE induces S phase arrest by activating the ATM/ATR-Chk1-Cdc25A signaling pathway in DLD-1 colon cancer cells. | 2020 Dec |
1 |
| 2 |
24380689 | Gap-filling and bypass at the replication fork are both active mechanisms for tolerance of low-dose ultraviolet-induced DNA damage in the human genome. | 2014 Feb |
1 |
| 3 |
23733185 | 4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway. | 2013 Jul 12 |
1 |
| 4 |
22753029 | CHK1 activity is required for continuous replication fork elongation but not stabilization of post-replicative gaps after UV irradiation. | 2012 Sep 1 |
1 |
| 5 |
21347609 | Premature chromosome condensation induced by caffeine, 2-aminopurine, staurosporine and sodium metavanadate in S-phase arrested HeLa cells is associated with a decrease in Chk1 phosphorylation, formation of phospho-H2AX and minor cytoskeletal rearrangements. | 2011 Mar |
1 |
| 6 |
21561856 | Caffeine promotes ultraviolet B-induced apoptosis in human keratinocytes without complete DNA repair. | 2011 Jul 1 |
1 |
| 7 |
20123862 | ATR/Chk1 pathway is essential for resumption of DNA synthesis and cell survival in UV-irradiated XP variant cells. | 2010 May 1 |
1 |
| 8 |
19242509 | ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine. | 2009 Jul |
3 |
| 9 |
17594092 | Caffeine markedly sensitizes human mesothelioma cell lines to pemetrexed. | 2008 Apr |
1 |
| 10 |
17292679 | ATR signaling mediates an S-phase checkpoint after inhibition of poly(ADP-ribose) polymerase activity. | 2007 Jun 1 |
1 |
| 11 |
17297454 | Irradiation-induced G2/M checkpoint response requires ERK1/2 activation. | 2007 Jul 12 |
1 |
| 12 |
17726372 | DNA damage-induced accumulation of centrosomal Chk1 contributes to its checkpoint function. | 2007 Oct 15 |
2 |
| 13 |
18088187 | p53-dependent Chk1 phosphorylation is required for maintenance of prolonged G2 Arrest. | 2007 Dec |
1 |
| 14 |
15676021 | Role of Chk1 and Chk2 in Ara-C-induced differentiation of human leukemia K562 cells. | 2005 Feb |
1 |
| 15 |
15975956 | Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells. | 2005 Nov |
1 |
| 16 |
15994368 | N-methyl-N'-nitro-N-nitrosoguanidine activates cell-cycle arrest through distinct mechanisms activated in a dose-dependent manner. | 2005 Oct |
1 |
| 17 |
12959929 | Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites. | 2004 Jan |
2 |
| 18 |
12660173 | Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint. | 2003 Apr 1 |
1 |
| 19 |
12676925 | Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents. | 2003 Jun 13 |
2 |
| 20 |
12678913 | Potentiation of DNA-damage-induced cytotoxicity by G2 checkpoint abrogators. | 2003 Jan |
1 |
| 21 |
12847089 | Caffeine inhibits checkpoint responses without inhibiting the ataxia-telangiectasia-mutated (ATM) and ATM- and Rad3-related (ATR) protein kinases. | 2003 Sep 26 |
1 |
| 22 |
13679850 | Induction of a caffeine-sensitive S-phase cell cycle checkpoint by psoralen plus ultraviolet A radiation. | 2003 Sep 18 |
1 |
| 23 |
11864911 | Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive. | 2002 Feb |
3 |
| 24 |
11912127 | An ATM-independent S-phase checkpoint response involves CHK1 pathway. | 2002 Mar 15 |
2 |
| 25 |
12429947 | UCN-01 (7-hydroxystauorsporine) blocks PMA-induced maturation and reciprocally promotes apoptosis in human myelomonocytic leukemia cells (U937). | 2002 Jul-Aug |
1 |
| 26 |
12446774 | An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage. | 2002 Dec |
1 |
| 27 |
11481475 | ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation. | 2001 Jul 31 |
1 |
| 28 |
11535615 | Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing. | 2001 Sep 3 |
1 |
| 29 |
10485486 | Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. | 1999 Sep 1 |
1 |