| Protein Name | adenosine A1 receptor |
|---|---|
| Organism | Mus musculus |
| Gene ID | 11539 |
| Gene Symbol | Adora1 |
| UniProt | Q60612 (AA1R_MOUSE), Q6AXD8 (Q6AXD8_MOUSE), Q8CAH1 (Q8CAH1_MOUSE), Q3URG8 (Q3URG8_MOUSE), Q3UYG0 (Q3UYG0_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
190
Total Number of Articles : 224 |
Description |
adenosine A1 receptor |
| Gene Summary |
Predicted to enable several functions, including G protein-coupled adenosine receptor activity; G-protein beta/gamma-subunit complex binding activity; and heterotrimeric G-protein binding activity. Involved in regulation of sensory perception of pain. Acts upstream of or within several processes, including excitatory postsynaptic potential; negative regulation of long-term synaptic depression; and negative regulation of mucus secretion. Located in dendritic spine. Is expressed in several structures, including adipose tissue; alimentary system; brain; genitourinary system; and heart. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ADORA1 (adenosine A1 receptor). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |