| 1 |
32725383 | Volume of Distribution is Unaffected by Metabolic Drug-Drug Interactions. | 2021 Feb |
1 |
| 2 |
35280254 | Pharmacokinetics of Caffeine: A Systematic Analysis of Reported Data for Application in Metabolic Phenotyping and Liver Function Testing. | 2021 |
1 |
| 3 |
31658882 | Impact of peripheral mutations on the access channels of human cytochrome P450 1A2. | 2020 Oct |
2 |
| 4 |
31744669 | Validation of a sensitive UHPLC-MS/MS method for cytochrome P450 probe substrates caffeine, tolbutamide, dextromethorphan, and alprazolam in human serum reveals drug contamination of serum used for research. | 2020 Feb 5 |
1 |
| 5 |
32219694 | In vitro inhibition of human cytochrome P450 enzymes by the novel atypical antipsychotic drug asenapine: a prediction of possible drug-drug interactions. | 2020 Jun |
2 |
| 6 |
32279279 | The atypical neuroleptics iloperidone and lurasidone inhibit human cytochrome P450 enzymes in vitro. Evaluation of potential metabolic interactions. | 2020 Dec |
1 |
| 7 |
32941854 | Asenapine and iloperidone decrease the expression of major cytochrome P450 enzymes CYP1A2 and CYP3A4 in human hepatocytes. A significance for drug-drug interactions during combined therapy. | 2020 Nov 1 |
2 |
| 8 |
31164617 | Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy. | 2019 May 13 |
1 |
| 9 |
28686070 | Effects of aging and rifampicin pretreatment on the pharmacokinetics of human cytochrome P450 probes caffeine, warfarin, omeprazole, metoprolol and midazolam in common marmosets genotyped for cytochrome P450 2C19. | 2018 Jul |
2 |
| 10 |
27273149 | Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects. | 2017 Jan |
1 |
| 11 |
27712037 | In vivo cytochrome P450 activity alterations in diabetic nonalcoholic steatohepatitis mice. | 2017 Feb |
1 |
| 12 |
26481538 | Inhibition of human cytochrome P450 isoenzymes by a phenothiazine neuroleptic levomepromazine: An in vitro study. | 2015 Dec |
2 |
| 13 |
22483397 | High-sensitivity liquid chromatography-tandem mass spectrometry for the simultaneous determination of five drugs and their cytochrome P450-specific probe metabolites in human plasma. | 2012 May 1 |
1 |
| 14 |
20532872 | Genetics of caffeine consumption and responses to caffeine. | 2010 Aug |
1 |
| 15 |
19422358 | Effects of Angelicae tenuissima radix, Angelicae dahuricae radix and Scutellariae radix extracts on cytochrome P450 activities in healthy volunteers. | 2009 Oct |
1 |
| 16 |
20002088 | Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6 and 3A. | 2009 Dec |
1 |
| 17 |
20081260 | Effect of diethyldithiocarbamate (DDC) and ticlopidine on CYP1A2 activity and caffeine metabolism: an in vitro comparative study with human cDNA-expressed CYP1A2 and liver microsomes. | 2009 Nov-Dec |
1 |
| 18 |
11956503 | Acute hypoxia and cytochrome P450-mediated hepatic drug metabolism in humans. | 2002 Apr |
1 |
| 19 |
8857078 | Biotransformation of caffeine by cDNA-expressed human cytochromes P-450. | 1996 |
1 |
| 20 |
8081318 | Caffeine and exercise: metabolism and performance. | 1994 Jun |
1 |
| 21 |
1808966 | [Effect of levonorgestrel and ethinyl estradiol and their combination on biotransformation reactions]. | 1991 |
2 |
| 22 |
1981505 | Quinolone inhibition of cytochrome P-450-dependent caffeine metabolism in human liver microsomes. | 1990 Nov-Dec |
3 |
| 23 |
2220168 | [Effect of a new gestagen--dienogest--and its combination with ethinyl estradiol on the activity of biotransformation reactions]. | 1990 |
2 |
| 24 |
3593412 | Biotransformation of caffeine by microsomes from human liver. Kinetics and inhibition studies. | 1987 Apr 15 |
2 |
| 25 |
3671445 | [The effect of intrahepatic cholestasis in pregnancy on various forms of cytochrome P-450-dependent biotransformation reactions]. | 1987 May |
1 |
| 26 |
3991787 | [Determination of caffeine and metamizole elimination in men and women with and without hormonal contraceptives as an in vivo method for characterization of various cytochrome P-450 subspecies]. | 1985 Jan |
1 |
| 27 |
4095131 | [Elimination of caffeine and metamizol in in vivo characterization of cytochrome P-450 dependent biotransformation reactions in aged humans]. | 1985 Nov |
1 |
| 28 |
4095132 | [The influence of chronic renal insufficiency on the demethylating activities of various cytochrome P-450 subspecies in humans]. | 1985 Nov |
2 |