Protein Name renin
Organism Rattus norvegicus
Gene ID 24715
Gene Symbol


UniProt P08424 (RENI_RAT)
Relationships Total Number of functionally related compound(s) : 940
Total Number of Articles : 2386


Gene Summary

Enables endopeptidase activity and insulin-like growth factor receptor binding activity. Involved in several processes, including peptide metabolic process; response to lipopolysaccharide; and response to purine-containing compound. Located in cytoplasm and extracellular space. Used to study hypertension. Biomarker of primary biliary cholangitis. Human ortholog(s) of this gene implicated in essential hypertension; familial juvenile hyperuricemic nephropathy; hand, foot and mouth disease; hypertension; and portal hypertension. Orthologous to human REN (renin). [provided by Alliance of Genome Resources, Apr 2022]

  • renin
  • angiotensinogenase
  • renin 1 structural
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