| Protein Name | renin |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24715 |
| Gene Symbol | Ren |
| UniProt | P08424 (RENI_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
940
Total Number of Articles : 2386 |
Description |
renin |
| Gene Summary |
Enables endopeptidase activity and insulin-like growth factor receptor binding activity. Involved in several processes, including angiotensin maturation; response to cGMP; and response to lipopolysaccharide. Located in extracellular space. Used to study hypertension. Biomarker of hypertension; metabolic dysfunction and alcohol associated liver disease; and primary biliary cholangitis. Human ortholog(s) of this gene implicated in autosomal dominant tubulointerstitial kidney disease 4; essential hypertension; hand, foot and mouth disease; hypertension; and portal hypertension. Orthologous to human REN (renin). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |