Protein Name carbonic anhydrase 2
Organism Rattus norvegicus
Gene ID 54231
Gene Symbol

Car2

UniProt P27139 (CAH2_RAT)
Relationships Total Number of functionally related compound(s) : 879
Total Number of Articles : 1175
Description

carbonic anhydrase 2

Gene Summary

Enables carbonate dehydratase activity. Involved in several processes, including positive regulation of bone resorption; positive regulation of cellular pH reduction; and positive regulation of osteoclast differentiation. Located in several cellular components, including apical part of cell; basolateral plasma membrane; and microvillus. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 3 and osteopetrosis. Orthologous to human CA2 (carbonic anhydrase 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • carbonic anhydrase 2
  • CA-II
  • carbonate dehydratase II
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Properties