Caffeine

ryanodine receptor 2 ; Homo sapiens







49 Article(s)
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1 33825858 Identification of loss-of-function RyR2 mutations associated with idiopathic ventricular fibrillation and sudden death. 2021 Apr 30 2
2 34022226 RyR2 disease mutations at the C-terminal domain intersubunit interface alter closed-state stability and channel activation. 2021 Jul 2
3 34648073 Cardiomyocyte Na+ and Ca2+ mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors. 2021 Oct 14 1
4 34950703 The Identification of a Novel Calcium-Dependent Link Between NAD+ and Glucose Deprivation-Induced Increases in Protein O-GlcNAcylation and ER Stress. 2021 2
5 31437535 A novel homozygous mutation in the TRDN gene causes a severe form of pediatric malignant ventricular arrhythmia. 2020 Feb 1
6 31918058 Luminal addition of non-permeant Eu3+ interferes with luminal Ca2+ regulation of the cardiac ryanodine receptor. 2020 Apr 1
7 32663189 Molecular characterization of the calcium release channel deficiency syndrome. 2020 Aug 6 1
8 32878990 The central domain of cardiac ryanodine receptor governs channel activation, regulation, and stability. 2020 Nov 13 2
9 30170228 Linking the heart and the brain: Neurodevelopmental disorders in patients with catecholaminergic polymorphic ventricular tachycardia. 2019 Feb 1
10 31278385 Modulation of cardiac ryanodine receptor 2 by calmodulin. 2019 Aug 1
11 31735119 Fibroblast growth factor 9 (FGF9) inhibits myogenic differentiation of C2C12 and human muscle cells. 2019 Dec 1
12 30036502 Negative chronotropism, positive inotropism and lusitropism of 3,5-di-t-butyl-4-hydroxyanisole (DTBHA) on rat heart preparations occur through reduction of RyR2 Ca2+ leak. 2018 Sep 2
13 30271978 A tryptophan residue in the caffeine-binding site of the ryanodine receptor regulates Ca2+ sensitivity. 2018 1
14 30356673 Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial Fibrillation. 2018 1
15 28736243 From insulin synthesis to secretion: Alternative splicing of type 2 ryanodine receptor gene is essential for insulin secretion in pancreatic β cells. 2017 Oct 2
16 26849106 Cardiac ryanodine receptor: Selectivity for alkaline earth metal cations points to the EF-hand nature of luminal binding sites. 2016 Jun 1
17 21320437 Single ryanodine receptor channel basis of caffeine's action on Ca2+ sparks. 2011 Feb 16 5
18 21483779 Calcium handling in human induced pluripotent stem cell derived cardiomyocytes. 2011 Apr 1 1
19 19554099 Receptor activated Ca(2+) release is inhibited by boric acid in prostate cancer cells. 2009 Jun 23 1
20 17950843 FK506-binding protein (FKBP12) regulates ryanodine receptor-evoked Ca2+ release in colonic but not aortic smooth muscle. 2008 Jun 1
21 17967164 Localization of PKA phosphorylation site, Ser(2030), in the three-dimensional structure of cardiac ryanodine receptor. 2008 Mar 1 2
22 18326664 ARVC-related mutations in divergent region 3 alter functional properties of the cardiac ryanodine receptor. 2008 Jun 2
23 18446524 Caffeine-inducible ATP release is mediated by Ca2+-signal transducing system from the endoplasmic reticulum to mitochondria. 2008 Jul 1
24 18518861 Caffeine induces Ca2+ release by reducing the threshold for luminal Ca2+ activation of the ryanodine receptor. 2008 Sep 15 7
25 17322175 Alternative splicing of ryanodine receptors modulates cardiomyocyte Ca2+ signaling and susceptibility to apoptosis. 2007 Mar 30 1
26 17452324 Localization of an NH(2)-terminal disease-causing mutation hot spot to the "clamp" region in the three-dimensional structure of the cardiac ryanodine receptor. 2007 Jun 15 3
27 16529557 Recognition and activation of ryanodine receptors by purines. 2006 1
28 16603686 KCa channel insensitivity to Ca2+ sparks underlies fractional uncoupling in newborn cerebral artery smooth muscle cells. 2006 Sep 1
29 16624262 The RyR2 central domain peptide DPc10 lowers the threshold for spontaneous Ca2+ release in permeabilized cardiomyocytes. 2006 Jun 1 1
30 17206514 Comparison of the effects exerted by luminal Ca2+ on the sensitivity of the cardiac ryanodine receptor to caffeine and cytosolic Ca2+. 2006 1
31 15845383 Differential Ca2+ sensitivity of RyR2 mutations reveals distinct mechanisms of channel dysfunction in sudden cardiac death. 2005 May 27 1
32 16175570 Disruption of endoplasmic reticulum calcium stores is involved in neuronal death induced by glycolysis inhibition in cultured hippocampal neurons. 2005 Oct 15 3
33 14593104 The predicted TM10 transmembrane sequence of the cardiac Ca2+ release channel (ryanodine receptor) is crucial for channel activation and gating. 2004 Jan 30 2
34 14634821 Ryanodine receptors in peritoneal mast cells: possible role in the modulation of exocytotic activity. 2004 Jan 2
35 15047862 Ryanodine receptor regulation by intramolecular interaction between cytoplasmic and transmembrane domains. 2004 Jun 1
36 15081811 Location of divergent region 2 on the three-dimensional structure of cardiac muscle ryanodine receptor/calcium release channel. 2004 Apr 30 2
37 12576471 Three-dimensional localization of divergent region 3 of the ryanodine receptor to the clamp-shaped structures adjacent to the FKBP binding sites. 2003 Apr 18 1
38 12919952 Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes. 2003 Sep 19 3
39 14505449 Sarcolemma agonist-induced interactions between InsP3 and ryanodine receptors in Ca2+ oscillations and waves in smooth muscle. 2003 Oct 1
40 14557272 Residue Gln4863 within a predicted transmembrane sequence of the Ca2+ release channel (ryanodine receptor) is critical for ryanodine interaction. 2003 Dec 19 1
41 12164316 Role of the sarcoplasmic reticulum in uterine smooth muscle. 2002 1
42 12169647 Enhanced basal activity of a cardiac Ca2+ release channel (ryanodine receptor) mutant associated with ventricular tachycardia and sudden death. 2002 Aug 9 1
43 12324472 Three-dimensional reconstruction of the recombinant type 2 ryanodine receptor and localization of its divergent region 1. 2002 Nov 29 3
44 11427530 Functional characterization of mutants in the predicted pore region of the rabbit cardiac muscle Ca(2+) release channel (ryanodine receptor isoform 2). 2001 Aug 24 1
45 11477079 Functionally separate intracellular Ca2+ stores in smooth muscle. 2001 Sep 28 1
46 11507100 Ryanodine sensitizes the Ca(2+) release channel (ryanodine receptor) to Ca(2+) activation. 2001 Oct 26 1
47 11600671 Calcium waves induced by hypertonic solutions in intact frog skeletal muscle fibres. 2001 Oct 15 1
48 10733962 Role of Mg(2+) in Ca(2+)-induced Ca(2+) release through ryanodine receptors of frog skeletal muscle: modulations by adenine nucleotides and caffeine. 2000 Apr 1
49 9312152 Modulation of cardiac ryanodine receptors by sorcin. 1997 Oct 3 1