Caffeine

checkpoint kinase 2 ; Homo sapiens







17 Article(s)
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1 26727128 Checkpoint Kinase 1 Activation Enhances Intestinal Epithelial Barrier Function via Regulation of Claudin-5 Expression. 2016 1
2 25872745 Hepatitis B virus X protein activates the ATM-Chk2 pathway and delays cell cycle progression. 2015 Aug 1
3 26521794 Caffeine Suppresses Apoptosis of Bladder Cancer RT4 Cells in Response to Ionizing Radiation by Inhibiting Ataxia Telangiectasia Mutated-Chk2-p53 Axis. 2015 Nov 5 3
4 22828439 The small molecule calactin induces DNA damage and apoptosis in human leukemia cells. 2012 Sep 1
5 19536869 Shallot and licorice constituent isoliquiritigenin arrests cell cycle progression and induces apoptosis through the induction of ATM/p53 and initiation of the mitochondrial system in human cervical carcinoma HeLa cells. 2009 Jul 1
6 19705844 Tricetin, a dietary flavonoid, inhibits proliferation of human breast adenocarcinoma mcf-7 cells by blocking cell cycle progression and inducing apoptosis. 2009 Sep 23 1
7 18511169 Kotomolide A arrests cell cycle progression and induces apoptosis through the induction of ATM/p53 and the initiation of mitochondrial system in human non-small cell lung cancer A549 cells. 2008 Jul 1
8 17727682 Soy-derived isoflavones inhibit the growth of adult T-cell leukemia cells in vitro and in vivo. 2007 Nov 1
9 16741947 ATR dependent activation of Chk2. 2006 Sep 2
10 15620706 Loss of RPA1 induces Chk2 phosphorylation through a caffeine-sensitive pathway. 2005 Jan 3 2
11 15676021 Role of Chk1 and Chk2 in Ara-C-induced differentiation of human leukemia K562 cells. 2005 Feb 1
12 15994368 N-methyl-N'-nitro-N-nitrosoguanidine activates cell-cycle arrest through distinct mechanisms activated in a dose-dependent manner. 2005 Oct 1
13 14757171 Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1. 2004 Feb 15 1
14 11535615 Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing. 2001 Sep 3 1
15 10744722 Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity. 2000 Apr 7 4
16 10809772 Distinct Chk2 activation pathways are triggered by genistein and DNA-damaging agents in human melanoma cells. 2000 May 19 1
17 10531013 Caffeine inhibits the checkpoint kinase ATM. 1999 Oct 7 2