| Protein Name | cytochrome P450, family 1, subfamily a, polypeptide 2 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24297 |
| Gene Symbol | Cyp1a2 |
| UniProt | P04799 (CP1A2_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
673
Total Number of Articles : 732 |
Description |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
| Gene Summary |
Enables nitrite reductase (NO-forming) activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Involved in several processes, including cellular response to copper ion; nitroglycerin metabolic process; and response to tetrachloromethane. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in mitochondrion. Biomarker of congestive heart failure and depressive disorder. Human ortholog(s) of this gene implicated in breast cancer; chronic obstructive pulmonary disease; endometrial cancer; and porphyria cutanea tarda. Orthologous to human CYP1A2 (cytochrome P450 family 1 subfamily A member 2). [provided by Alliance of Genome Resources, Jul 2025] |
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