Protein Name Fos proto-oncogene, AP-1 transcription factor subunit
Organism Rattus norvegicus
Gene ID 314322
Gene Symbol

Fos

UniProt P12841 (FOS_RAT)
Relationships Total Number of functionally related compound(s) : 1662
Total Number of Articles : 4438
Description

Fos proto-oncogene, AP-1 transcription factor subunit

Gene Summary

Enables DNA binding activity; DNA-binding transcription factor activity; and promoter-specific chromatin binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; learning or memory; and nervous system development. Located in endoplasmic reticulum; nuclear matrix; and nucleoplasm. Used to study alcohol dependence; alcohol use disorder; gastric ulcer; and morphine dependence. Biomarker of several diseases, including alcohol dependence; alcohol use disorder; artery disease (multiple); brain disease (multiple); and drug dependence (multiple). Orthologous to human FOS (Fos proto-oncogene, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • protein c-Fos
  • FBJ murine osteosarcoma viral oncogene homolog
  • FBJ osteosarcoma oncogene
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Properties