Protein Name | N-acetyltransferase 2 |
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Organism | Homo sapiens |
Gene ID | 10 |
Gene Symbol | NAT2 |
UniProt | P11245 (ARY2_HUMAN), A4Z6T7 (A4Z6T7_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
326
Total Number of Articles : 534 |
Description |
N-acetyltransferase 2 |
Gene Summary |
This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second polymorphic arylamine N-acetyltransferase gene (NAT1), is located near this gene (NAT2). [provided by RefSeq, Sep 2019] |
synonyms |
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Properties | |