Protein Name cytochrome P450, family 1, subfamily a, polypeptide 2
Organism Mus musculus
Gene ID 13077
Gene Symbol


UniProt P00186 (CP1A2_MOUSE), B6VGH4 (B6VGH4_MOUSE)
Relationships Total Number of functionally related compound(s) : 215
Total Number of Articles : 257

cytochrome P450, family 1, subfamily a, polypeptide 2

Gene Summary

Enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Acts upstream of or within several processes, including cellular response to cadmium ion; dibenzo-p-dioxin metabolic process; and hydrogen peroxide biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in liver. Human ortholog(s) of this gene implicated in breast cancer; chronic obstructive pulmonary disease; endometrial cancer; and porphyria cutanea tarda. Orthologous to human CYP1A2 (cytochrome P450 family 1 subfamily A member 2). [provided by Alliance of Genome Resources, Apr 2022]

  • cytochrome P450 1A2
  • cholesterol 25-hydroxylase
  • cytochrome P450 family 1 subfamily a polypeptide 1
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