Caffeine

mechanistic target of rapamycin kinase ; Homo sapiens







13 Article(s)
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1 34371919 Caffeine Has Different Immunomodulatory Effect on the Cytokine Expression and NLRP3 Inflammasome Function in Various Human Macrophage Subpopulations. 2021 Jul 14 1
2 31955628 Caffeine Potentiates Ethanol-Induced Neurotoxicity Through mTOR/p70S6K/4E-BP1 Inhibition in SH-SY5Y Cells. 2020 Mar/Apr 4
3 32104547 Caffeine and its main targets of colorectal cancer. 2020 Feb 15 2
4 30875347 Methylxanthine derivatives promote autophagy in gastric cancer cells targeting PTEN. 2019 Apr 3
5 28569556 Guaraná, a Highly Caffeinated Food, Presents in vitro Antitumor Activity in Colorectal and Breast Cancer Cell Lines by Inhibiting AKT/mTOR/S6K and MAPKs Pathways. 2017 Jul 1
6 26384306 Caffeine affects the biological responses of human hematopoietic cells of myeloid lineage via downregulation of the mTOR pathway and xanthine oxidase activity. 2015 Oct 6 3
7 23929677 Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice. 2014 Apr 1
8 25482947 mTOR inhibitors blunt the p53 response to nucleolar stress by regulating RPL11 and MDM2 levels. 2014 1
9 22993301 Caffeine induces apoptosis of osteosarcoma cells by inhibiting AKT/mTOR/S6K, NF-κB and MAPK pathways. 2012 Sep 2
10 21081844 Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition. 2011 Feb 2
11 21940847 Caffeine modulates phosphorylation of insulin receptor substrate-1 and impairs insulin signal transduction in rat skeletal muscle. 2011 Dec 1
12 20812900 Updates of mTOR inhibitors. 2010 Sep 1
13 19785652 Regulation by FK506 and rapamycin of Ca2+ release from the sarcoplasmic reticulum in vascular smooth muscle: the role of FK506 binding proteins and mTOR. 2009 Oct 1