Caffeine

ryanodine receptor 1 ; Homo sapiens







78 Article(s)
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Pub. Year
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1 34455637 Mapping co-regulatory interactions among ligand-binding sites in ryanodine receptor 1. 2022 Feb 1
2 33490280 Effects of Remimazolam and Propofol on Ca2+ Regulation by Ryanodine Receptor 1 with Malignant Hyperthermia Mutation. 2021 1
3 34352272 Structural and functional interactions between the Ca2+-, ATP-, and caffeine-binding sites of skeletal muscle ryanodine receptor (RyR1). 2021 Sep 11
4 32499888 The Arianna thread: the matching of S-100 family with the RyR's muscle receptor. 2020 Apr 7 1
5 32535660 Functional analysis of newly identified RYR1 variants in patients susceptible to malignant hyperthermia. 2020 Oct 1
6 31166712 A central core disease mutation in the Ca2+-binding site of skeletal muscle ryanodine receptor impairs single-channel regulation. 2019 Aug 1 5
7 29344738 Genetic and functional analysis of the RYR1 mutation p.Thr84Met revealed a susceptibility to malignant hyperthermia. 2018 Apr 2
8 30271978 A tryptophan residue in the caffeine-binding site of the ryanodine receptor regulates Ca2+ sensitivity. 2018 1
9 30389846 Caffeine chelates calcium in the lumen of the endoplasmic reticulum. 2018 Nov 28 1
10 28403410 Assessing the pathogenicity of RYR1 variants in malignant hyperthermia. 2017 Apr 1 1
11 28713161 Functional expression of the Ca2+ signaling machinery in human embryonic stem cells. 2017 Dec 2
12 27199668 Mediation of Autophagic Cell Death by Type 3 Ryanodine Receptor (RyR3) in Adult Hippocampal Neural Stem Cells. 2016 1
13 27235390 K201 (JTV519) is a Ca2+-Dependent Blocker of SERCA and a Partial Agonist of Ryanodine Receptors in Striated Muscle. 2016 Aug 1
14 27717822 Inhibiting c-Jun N-terminal kinase partially attenuates caffeine-dependent cell death without alleviating the caffeine-induced reduction in mitochondrial respiration in C2C12 skeletal myotubes. 2016 Nov 4 3
15 25998124 Channel Gating Dependence on Pore Lining Helix Glycine Residues in Skeletal Muscle Ryanodine Receptor. 2015 Jul 10 2
16 24423447 Eudistomin D and penaresin derivatives as modulators of ryanodine receptor channels and sarcoplasmic reticulum Ca2+ ATPase in striated muscle. 2014 Apr 3
17 24972488 Characterization of ryanodine receptor type 1 single channel activity using "on-nucleus" patch clamp. 2014 Aug 1
18 23558838 Ryanodine receptor type 1 gene variants in the malignant hyperthermia-susceptible population of the United States. 2013 May 1
19 22784666 Switch from ER-mitochondrial to SR-mitochondrial calcium coupling during muscle differentiation. 2012 Nov 1
20 22842488 Store-independent pathways for cytosolic STIM1 clustering in the regulation of store-operated Ca(2+) influx. 2012 Oct 15 1
21 22948152 Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes. 2012 Oct 26 2
22 21862589 Role of amino-terminal half of the S4-S5 linker in type 1 ryanodine receptor (RyR1) channel gating. 2011 Oct 14 1
23 21918424 Identical de novo mutation in the type 1 ryanodine receptor gene associated with fatal, stress-induced malignant hyperthermia in two unrelated families. 2011 Nov 4
24 21472222 Modulation of ryanodine receptor Ca2+ channels (Review). 2010 Mar-Apr 1
25 18954145 Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 and 2. 2009 Jan 1
26 19636685 Effects of small molecule modulators on ATP binding to skeletal ryanodine receptor. 2009 Jun 3
27 19685112 Functional analysis of ryanodine receptor type 1 p.R2508C mutation in exon 47. 2009 2
28 18096513 Allosterically coupled calcium and magnesium binding sites are unmasked by ryanodine receptor chimeras. 2008 Feb 22 1
29 18406528 Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture. 2008 May 16 3
30 17259277 Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+. 2007 Apr 15 1
31 17446473 Na/Ca exchange: regulator of intracellular calcium and source of arrhythmias in the heart. 2007 Mar 1
32 16945924 Azumolene inhibits a component of store-operated calcium entry coupled to the skeletal muscle ryanodine receptor. 2006 Nov 3 1
33 17092484 Occurrence of atypical Ca2+ transients in triadin-binding deficient-RYR1 mutants. 2006 Dec 29 1
34 15677376 Postulated role of interdomain interactions within the type 1 ryanodine receptor in the low gain of Ca2+-induced Ca2+ release activity of mammalian skeletal muscle sarcoplasmic reticulum. 2005 Jun 1
35 13679303 Conformational coupling of DHPR and RyR1 in skeletal myotubes is influenced by long-range allosterism: evidence for a negative regulatory module. 2004 Jan 1
36 14592807 All three ryanodine receptor isoforms generate rapid cooling responses in muscle cells. 2004 Mar 1
37 14600284 Non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95) amplifies ionotropic glutamate receptor signaling in embryonic cerebellar granule neurons by a mechanism involving ryanodine receptors. 2004 Jan 1
38 14706290 The calmodulin binding region of the skeletal ryanodine receptor acts as a self-modulatory domain. 2004 Feb 1
39 15201141 Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III-IV loop on skeletal muscle EC coupling. 2004 Oct 1
40 15269663 [Genetic of diseases by abnormal functioning of the skeletal muscle-calcium releasing complex]. 2004 May 1
41 15299003 Effect of ryanodine receptor mutations on interleukin-6 release and intracellular calcium homeostasis in human myotubes from malignant hyperthermia-susceptible individuals and patients affected by central core disease. 2004 Oct 15 2
42 12921667 [Expression and role of inositol 1,4,5-trisphosphate receptor and ryanodine receptor in a human lens epithelial cell line]. 2003 Jul 1
43 14641996 Calcium release from sarcoplasmic reticulum is facilitated in human myotubes derived from carriers of the ryanodine receptor type 1 mutations Ile2182Phe and Gly2375Ala. 2003 Fall 2
44 11682466 T-tubule depolarization-induced local events in the ryanodine receptor, as monitored with the fluorescent conformational probe incorporated by mediation of peptide A. 2002 Jan 11 1
45 12045220 RyR1 and RyR3 isoforms provide distinct intracellular Ca2+ signals in HEK 293 cells. 2002 Jun 15 1
46 12124989 RYR1 mutations causing central core disease are associated with more severe malignant hyperthermia in vitro contracture test phenotypes. 2002 Aug 1
47 12151923 Results of contracture tests with halothane, caffeine, and ryanodine depend on different malignant hyperthermia-associated ryanodine receptor gene mutations. 2002 Aug 2
48 12213830 Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors). 2002 Nov 1 1
49 12220451 Increased sensitivity to 4-chloro-m-cresol and caffeine in primary myotubes from malignant hyperthermia susceptible individuals carrying the ryanodine receptor 1 Thr2206Met (C6617T) mutation. 2002 Aug 1
50 12223488 Homer regulates gain of ryanodine receptor type 1 channel complex. 2002 Nov 22 1